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Surgical Treatment of de novo Metastatic Breast Cancer

Publication ,  Journal Article
Rooney, MM; Miller, KN; Rosenberger, LH; Plichta, JK
Published in: Current Breast Cancer Reports
September 1, 2022

Purpose of review: De novo metastatic breast cancer (dnMBC) accounts for approximately 6% of all new breast cancers each year. While the survival benefits from removing the primary tumor in patients with MBC remain unclear, many patients still undergo surgery. The purpose of this review is to evaluate recent retrospective and prospective studies that examine the role of surgical resection of primary tumors for patients with dnMBC. Recent Findings: Many retrospective analyses have suggested a survival benefit associated with surgery. However, recent prospective randomized clinical trials, both nationally and internationally, have not consistently demonstrated a survival benefit for all patients, although subgroup analyses suggest a possible survival benefit for certain subpopulations. Summary: The role of surgery in the treatment of dnMBC is not fully defined. Certain subgroups may benefit from surgery as an option for the local–regional treatment of their cancers. Ongoing prospective clinical trials are evaluating these questions.

Duke Scholars

Published In

Current Breast Cancer Reports

DOI

EISSN

1943-4596

ISSN

1943-4588

Publication Date

September 1, 2022

Volume

14

Issue

3

Start / End Page

83 / 92

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
 

Citation

APA
Chicago
ICMJE
MLA
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Rooney, M. M., Miller, K. N., Rosenberger, L. H., & Plichta, J. K. (2022). Surgical Treatment of de novo Metastatic Breast Cancer. Current Breast Cancer Reports, 14(3), 83–92. https://doi.org/10.1007/s12609-022-00448-0
Rooney, M. M., K. N. Miller, L. H. Rosenberger, and J. K. Plichta. “Surgical Treatment of de novo Metastatic Breast Cancer.” Current Breast Cancer Reports 14, no. 3 (September 1, 2022): 83–92. https://doi.org/10.1007/s12609-022-00448-0.
Rooney MM, Miller KN, Rosenberger LH, Plichta JK. Surgical Treatment of de novo Metastatic Breast Cancer. Current Breast Cancer Reports. 2022 Sep 1;14(3):83–92.
Rooney, M. M., et al. “Surgical Treatment of de novo Metastatic Breast Cancer.” Current Breast Cancer Reports, vol. 14, no. 3, Sept. 2022, pp. 83–92. Scopus, doi:10.1007/s12609-022-00448-0.
Rooney MM, Miller KN, Rosenberger LH, Plichta JK. Surgical Treatment of de novo Metastatic Breast Cancer. Current Breast Cancer Reports. 2022 Sep 1;14(3):83–92.
Journal cover image

Published In

Current Breast Cancer Reports

DOI

EISSN

1943-4596

ISSN

1943-4588

Publication Date

September 1, 2022

Volume

14

Issue

3

Start / End Page

83 / 92

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis