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Attenuation of actinic prurigo eruptions with Polypodium leucotomos supplementation.

Publication ,  Journal Article
Stump, M; Dhinsa, H; Powers, J; Stone, M
Published in: Pediatr Dermatol
January 2022

Actinic prurigo is a rare pruritic photodermatosis. We report the use of Polypodium leucotomos extract in an 11-year-old female patient with actinic prurigo, resulting in a significant attenuation of her disease without development of adverse effects to date. Polypodium leucotomos exerts a pleiotropic immunomodulatory and antioxidant effect by shifting the balance from pro- to an antiinflammatory cytokine environment. This counteracts the effects of UV-induced cellular damage characteristic of photodermatoses.

Duke Scholars

Published In

Pediatr Dermatol

DOI

EISSN

1525-1470

Publication Date

January 2022

Volume

39

Issue

1

Start / End Page

145 / 146

Location

United States

Related Subject Headings

  • Skin Diseases, Genetic
  • Prurigo
  • Polypodium
  • Plant Extracts
  • Photosensitivity Disorders
  • Humans
  • Female
  • Dietary Supplements
  • Dermatology & Venereal Diseases
  • Child
 

Citation

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ICMJE
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Stump, M., Dhinsa, H., Powers, J., & Stone, M. (2022). Attenuation of actinic prurigo eruptions with Polypodium leucotomos supplementation. Pediatr Dermatol, 39(1), 145–146. https://doi.org/10.1111/pde.14876
Stump, Madeliene, Harpinder Dhinsa, Jennifer Powers, and Mary Stone. “Attenuation of actinic prurigo eruptions with Polypodium leucotomos supplementation.Pediatr Dermatol 39, no. 1 (January 2022): 145–46. https://doi.org/10.1111/pde.14876.
Stump M, Dhinsa H, Powers J, Stone M. Attenuation of actinic prurigo eruptions with Polypodium leucotomos supplementation. Pediatr Dermatol. 2022 Jan;39(1):145–6.
Stump, Madeliene, et al. “Attenuation of actinic prurigo eruptions with Polypodium leucotomos supplementation.Pediatr Dermatol, vol. 39, no. 1, Jan. 2022, pp. 145–46. Pubmed, doi:10.1111/pde.14876.
Stump M, Dhinsa H, Powers J, Stone M. Attenuation of actinic prurigo eruptions with Polypodium leucotomos supplementation. Pediatr Dermatol. 2022 Jan;39(1):145–146.
Journal cover image

Published In

Pediatr Dermatol

DOI

EISSN

1525-1470

Publication Date

January 2022

Volume

39

Issue

1

Start / End Page

145 / 146

Location

United States

Related Subject Headings

  • Skin Diseases, Genetic
  • Prurigo
  • Polypodium
  • Plant Extracts
  • Photosensitivity Disorders
  • Humans
  • Female
  • Dietary Supplements
  • Dermatology & Venereal Diseases
  • Child