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PET Imaging of Dementia: Update 2022.

Publication ,  Journal Article
Burkett, BJ; Babcock, JC; Lowe, VJ; Graff-Radford, J; Subramaniam, RM; Johnson, DR
Published in: Clin Nucl Med
September 1, 2022

PET imaging plays an essential role in achieving earlier and more specific diagnoses of dementia syndromes, important for clinical prognostication and optimal medical management. This has become especially vital with the recent development of pathology-specific disease-modifying therapy for Alzheimer disease, which will continue to evolve and require methods to select appropriate treatment candidates. Techniques that began as research tools such as amyloid and tau PET have now entered clinical use, making nuclear medicine physicians and radiologists essential members of the care team. This review discusses recent changes in the understanding of dementia and examines the roles of nuclear medicine imaging in clinical practice. Within this framework, multiple cases will be shown to illustrate a systematic approach of FDG PET interpretation and integration of PET imaging of specific molecular pathology including dopamine transporters, amyloid, and tau. The approach presented here incorporates contemporary understanding of both common and uncommon dementia syndromes, intended as an updated practical guide to assist with the sophisticated interpretation of nuclear medicine examinations in the context of this rapidly and continually developing area of imaging.

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Published In

Clin Nucl Med

DOI

EISSN

1536-0229

Publication Date

September 1, 2022

Volume

47

Issue

9

Start / End Page

763 / 773

Location

United States

Related Subject Headings

  • Syndrome
  • Positron-Emission Tomography
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Dementia
  • Brain
  • Amyloid
  • Alzheimer Disease
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Burkett, B. J., Babcock, J. C., Lowe, V. J., Graff-Radford, J., Subramaniam, R. M., & Johnson, D. R. (2022). PET Imaging of Dementia: Update 2022. Clin Nucl Med, 47(9), 763–773. https://doi.org/10.1097/RLU.0000000000004251
Burkett, Brian J., Jeffrey C. Babcock, Val J. Lowe, Jonathan Graff-Radford, Rathan M. Subramaniam, and Derek R. Johnson. “PET Imaging of Dementia: Update 2022.Clin Nucl Med 47, no. 9 (September 1, 2022): 763–73. https://doi.org/10.1097/RLU.0000000000004251.
Burkett BJ, Babcock JC, Lowe VJ, Graff-Radford J, Subramaniam RM, Johnson DR. PET Imaging of Dementia: Update 2022. Clin Nucl Med. 2022 Sep 1;47(9):763–73.
Burkett, Brian J., et al. “PET Imaging of Dementia: Update 2022.Clin Nucl Med, vol. 47, no. 9, Sept. 2022, pp. 763–73. Pubmed, doi:10.1097/RLU.0000000000004251.
Burkett BJ, Babcock JC, Lowe VJ, Graff-Radford J, Subramaniam RM, Johnson DR. PET Imaging of Dementia: Update 2022. Clin Nucl Med. 2022 Sep 1;47(9):763–773.

Published In

Clin Nucl Med

DOI

EISSN

1536-0229

Publication Date

September 1, 2022

Volume

47

Issue

9

Start / End Page

763 / 773

Location

United States

Related Subject Headings

  • Syndrome
  • Positron-Emission Tomography
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Dementia
  • Brain
  • Amyloid
  • Alzheimer Disease
  • 3202 Clinical sciences
  • 1103 Clinical Sciences