Community-acquired multi-drug resistant Escherichia coli in a patient presenting with pyelonephritis

TEM and SHV extended-spectrum β-lactamases (ESBLs) used to be the dominant ESBLs in the 1990s, but more recently, the emergence of CTX-M enzymes have been increasingly recognized worldwide. Gram-negative rods harboring these β-lactamases represent a significant challenge to both clinicians and microbiologists due to the increasing number of reported cases of bacteria-producing ESBLs from the community. We highlight the case of a CTX-M-15-producing Escherichia coli urinary tract isolate causing infection in a patient from the community with no significant risk factors for acquiring E. coli harboring blaCTX-M. © 2011 by Lippincott Williams & Wilkins.

Duke Scholars

Author Amreen Dinani Medicine, Gastroenterology