HLA-G and HLA-C at the feto-maternal interface: lessons learned from pathogenic viruses.
Publication
, Journal Article
Schust, DJ; Tortorella, D; Ploegh, HL
Published in: Semin Cancer Biol
February 1999
Immunoevasive viruses which effect antigen presentation by class I major histocompatibility complex (MHC) molecules have helped to broaden our understanding of the intracellular transport and processing of HLA-G and HLA-C in the placenta. Cellular infection with herpes simplex virus (HSV) and human cytomegalovirus (HCMV) are each associated with the downregulation of surface expression of HLA-A and -B, albeit by remarkably distinct mechanisms. Investigations on the effects of HSV and HCMV infection on HLA-G and HLA-C in the trophoblast have revealed both hypothesized similarities and surprising differences between trophoblast and classical class I products.
Duke Scholars
Published In
Semin Cancer Biol
DOI
ISSN
1044-579X
Publication Date
February 1999
Volume
9
Issue
1
Start / End Page
37 / 46
Location
England
Related Subject Headings
- Simplexvirus
- Pregnancy
- Oncology & Carcinogenesis
- Maternal-Fetal Exchange
- Humans
- Histocompatibility Antigens Class I
- HLA-G Antigens
- HLA-C Antigens
- HLA Antigens
- Female
Citation
APA
Chicago
ICMJE
MLA
NLM
Schust, D. J., Tortorella, D., & Ploegh, H. L. (1999). HLA-G and HLA-C at the feto-maternal interface: lessons learned from pathogenic viruses. Semin Cancer Biol, 9(1), 37–46. https://doi.org/10.1006/scbi.1998.0106
Schust, D. J., D. Tortorella, and H. L. Ploegh. “HLA-G and HLA-C at the feto-maternal interface: lessons learned from pathogenic viruses.” Semin Cancer Biol 9, no. 1 (February 1999): 37–46. https://doi.org/10.1006/scbi.1998.0106.
Schust DJ, Tortorella D, Ploegh HL. HLA-G and HLA-C at the feto-maternal interface: lessons learned from pathogenic viruses. Semin Cancer Biol. 1999 Feb;9(1):37–46.
Schust, D. J., et al. “HLA-G and HLA-C at the feto-maternal interface: lessons learned from pathogenic viruses.” Semin Cancer Biol, vol. 9, no. 1, Feb. 1999, pp. 37–46. Pubmed, doi:10.1006/scbi.1998.0106.
Schust DJ, Tortorella D, Ploegh HL. HLA-G and HLA-C at the feto-maternal interface: lessons learned from pathogenic viruses. Semin Cancer Biol. 1999 Feb;9(1):37–46.
Published In
Semin Cancer Biol
DOI
ISSN
1044-579X
Publication Date
February 1999
Volume
9
Issue
1
Start / End Page
37 / 46
Location
England
Related Subject Headings
- Simplexvirus
- Pregnancy
- Oncology & Carcinogenesis
- Maternal-Fetal Exchange
- Humans
- Histocompatibility Antigens Class I
- HLA-G Antigens
- HLA-C Antigens
- HLA Antigens
- Female