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Extracranial-intracranial bypass surgery: hemodynamic and metabolic effects.

Publication ,  Journal Article
Powers, WJ; Martin, WR; Herscovitch, P; Raichle, ME; Grubb, RL
Published in: Neurology
September 1984

After superficial temporal artery-middle cerebral artery bypass, cerebral blood flow (CBF) in the operated hemisphere increased in 6 of 17 patients. Preoperatively, the symptomatic hemisphere showed lower CBF in all six, lower oxygen metabolism in five, higher blood volume in four, and higher oxygen extraction in two. With the postoperative increase in hemispheric CBF, there was a decrease in oxygen extraction, but no change in blood volume or oxygen metabolism. In these patients, chronic regional hypoperfusion followed major vascular occlusion. Compensatory responses included dilation of intraparenchymal vessels and increased transport of oxygen from blood to tissue. These changes were partially reversed by cerebral revascularization.

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Published In

Neurology

DOI

ISSN

0028-3878

Publication Date

September 1984

Volume

34

Issue

9

Start / End Page

1168 / 1174

Location

United States

Related Subject Headings

  • Tomography, Emission-Computed
  • Oxygen Consumption
  • Oxygen
  • Neurology & Neurosurgery
  • Middle Aged
  • Ischemic Attack, Transient
  • Humans
  • Cerebrovascular Circulation
  • Cerebral Revascularization
  • Cerebral Infarction
 

Citation

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Powers, W. J., Martin, W. R., Herscovitch, P., Raichle, M. E., & Grubb, R. L. (1984). Extracranial-intracranial bypass surgery: hemodynamic and metabolic effects. Neurology, 34(9), 1168–1174. https://doi.org/10.1212/wnl.34.9.1168
Powers, W. J., W. R. Martin, P. Herscovitch, M. E. Raichle, and R. L. Grubb. “Extracranial-intracranial bypass surgery: hemodynamic and metabolic effects.Neurology 34, no. 9 (September 1984): 1168–74. https://doi.org/10.1212/wnl.34.9.1168.
Powers WJ, Martin WR, Herscovitch P, Raichle ME, Grubb RL. Extracranial-intracranial bypass surgery: hemodynamic and metabolic effects. Neurology. 1984 Sep;34(9):1168–74.
Powers, W. J., et al. “Extracranial-intracranial bypass surgery: hemodynamic and metabolic effects.Neurology, vol. 34, no. 9, Sept. 1984, pp. 1168–74. Pubmed, doi:10.1212/wnl.34.9.1168.
Powers WJ, Martin WR, Herscovitch P, Raichle ME, Grubb RL. Extracranial-intracranial bypass surgery: hemodynamic and metabolic effects. Neurology. 1984 Sep;34(9):1168–1174.

Published In

Neurology

DOI

ISSN

0028-3878

Publication Date

September 1984

Volume

34

Issue

9

Start / End Page

1168 / 1174

Location

United States

Related Subject Headings

  • Tomography, Emission-Computed
  • Oxygen Consumption
  • Oxygen
  • Neurology & Neurosurgery
  • Middle Aged
  • Ischemic Attack, Transient
  • Humans
  • Cerebrovascular Circulation
  • Cerebral Revascularization
  • Cerebral Infarction