Skip to main content

Oxytocin and socioemotional aging: Current knowledge and future trends.

Publication ,  Journal Article
Ebner, NC; Maura, GM; Macdonald, K; Westberg, L; Fischer, H
Published in: Front Hum Neurosci
2013

The oxytocin (OT) system is involved in various aspects of social cognition and prosocial behavior. Specifically, OT has been examined in the context of social memory, emotion recognition, cooperation, trust, empathy, and bonding, and-though evidence is somewhat mixed-intranasal OT appears to benefit aspects of socioemotional functioning. However, most of the extant data on aging and OT is from animal research and human OT research has focused largely on young adults. As such, though we know that various socioemotional capacities change with age, we know little about whether age-related changes in the OT system may underlie age-related differences in socioemotional functioning. In this review, we take a genetic-neuro-behavioral approach and evaluate current evidence on age-related changes in the OT system as well as the putative effects of these alterations on age-related socioemotional functioning. Looking forward, we identify informational gaps and propose an Age-Related Genetic, Neurobiological, Sociobehavioral Model of Oxytocin (AGeNeS-OT model) which may structure and inform investigations into aging-related genetic, neural, and sociocognitive processes related to OT. As an exemplar of the use of the model, we report exploratory data suggesting differences in socioemotional processing associated with genetic variation in the oxytocin receptor gene (OXTR) in samples of young and older adults. Information gained from this arena has translational potential in depression, social stress, and anxiety-all of which have high relevance in aging-and may contribute to reducing social isolation and improving well-being of individuals across the lifespan.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Front Hum Neurosci

DOI

ISSN

1662-5161

Publication Date

2013

Volume

7

Start / End Page

487

Location

Switzerland

Related Subject Headings

  • Experimental Psychology
  • 5204 Cognitive and computational psychology
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1701 Psychology
  • 1109 Neurosciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ebner, N. C., Maura, G. M., Macdonald, K., Westberg, L., & Fischer, H. (2013). Oxytocin and socioemotional aging: Current knowledge and future trends. Front Hum Neurosci, 7, 487. https://doi.org/10.3389/fnhum.2013.00487
Ebner, Natalie C., Gabriela M. Maura, Kai Macdonald, Lars Westberg, and Håkan Fischer. “Oxytocin and socioemotional aging: Current knowledge and future trends.Front Hum Neurosci 7 (2013): 487. https://doi.org/10.3389/fnhum.2013.00487.
Ebner NC, Maura GM, Macdonald K, Westberg L, Fischer H. Oxytocin and socioemotional aging: Current knowledge and future trends. Front Hum Neurosci. 2013;7:487.
Ebner, Natalie C., et al. “Oxytocin and socioemotional aging: Current knowledge and future trends.Front Hum Neurosci, vol. 7, 2013, p. 487. Pubmed, doi:10.3389/fnhum.2013.00487.
Ebner NC, Maura GM, Macdonald K, Westberg L, Fischer H. Oxytocin and socioemotional aging: Current knowledge and future trends. Front Hum Neurosci. 2013;7:487.

Published In

Front Hum Neurosci

DOI

ISSN

1662-5161

Publication Date

2013

Volume

7

Start / End Page

487

Location

Switzerland

Related Subject Headings

  • Experimental Psychology
  • 5204 Cognitive and computational psychology
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1701 Psychology
  • 1109 Neurosciences