Stereoacuity after wavefront-guided photorefractive keratectomy in anisometropia

Purpose: To determine changes in stereoacuity in anisometropic myopic eyes after photorefractive keratectomy (PRK). Methods: Myopic patients with at least 1 diopter (D) of anisometropia in sphere, astigmatism, or spherical equivalent who were referred to our hospital for excimer refractive surgery were enrolled as a prospective sequential interventional case series. All patients underwent wavefront-guided photorefractive keratectomy (WFG-PRK) using the Technolas Perfect Vision (217z) Excimer laser machine. changes in binocular stereoacuity were evaluated using the TNO and Butterfly stereoacuity tests before and at 2 weeks, 1 month, and 3 months after the operation. Results: Between January and November 2015, a total of 98 eyes of 49 patients (71.4% men) with a mean age of 28 ± 5.5 years, mean myopia of -3.32 ± 1.74 D, and mean astigmatism of 1.3 ± 1.3 D were enrolled in this study. Preoperative mean stereoacuity values were 102 ± 103.44 and 56.8 ± 41 seconds of arc (s/arc)as measured by the TNO and Butterfly stereoacuity tests. Mean stereoacuity improved to 90 ± 110.52 s/arc (P = 0.009) and 56.5 ± 41.3 s/arc (P = 0.80), respectively, 6 months after WFG-PRK. Overall improvement in stereoacuity was 10.2% and 6.12% according to the TNO and Butterfly stereoacuity tests, respectively. Conclusion: Stereoacuity improves after WFG-PRK for treatment of anisometropic myopia. This improvement is more accurately detectable by the TNO than the Butterfly stereoacuity test. Karimian Farid 1 Ocular Tissue Engineering Research center; Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran Ownagh Vahid 2 Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran Amiri Mohammad 3 Department of Optometry, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran Tabatabaee Seyed 4 Department of Biostatistics, Shahid Beheshti University of Medical Sciences, Tehran Dadbin Nooshin 5 Negah Eye Center, Tehran Kaufman FL, Alm A, Adler FH. Stereopsis in: Adler's physiology of eye: clinical Application, 10th Ed. St Louis: Mosby, 2003;. p. 354-362. Noorden GK von. Binocular vision and ocular motility: Theory and management of strabismus, 5th Ed. St Louis: Mosby; 1996. p. 175-178. Merriam WW, Ellis FD, Helveston EM. congenital blepharoptosis, anisomertopia, and amblyopia. Am J Ophthalmol 1980;89:401-407. Beneish R, Williams F, Polomeno Rc, Little JM, Ramsey B. Unilateral congenital ptosis and amblyopia. can J Ophthalmol 1983;18:127-130. Duke-Elder S. System of Ophthalmology. London: Mosby; 1972. p. 457-462. De Donato LM, Rouse MW. Refractive anisometropia. Am Opt Assoc 1982;53:489-490. Sanfilippo S, Muchnick RS, Schlossman A. Preliminary observations on high anisometropia. Am Orthoptic J 1978;28:127-129. Kushner BJ. concern about the pediatric eye disease investigator group 2-year follow-up study. Arch Ophthalmol 2005;123:1615-1616. Duling k, Wick B. Binocular vision complications after radial keratotomy. Am J Optom Physiol Opt 1988;65:215-223. Scheiman MM, Rouse MW. Optometric management of learning-related vision problems. Mosby; 1994. p. 556-563. Rouse M. Optometric assessment of visual efficiency problems. In Scheiman MM, Rouse MW. Optometric management of learning-related vision problems. Mosby; 1994. p. 632-637. Donders Fc. On the anomalies of accommodation and refraction of the eye. Hatton Garden; 1864. p. 342-348. Wick B, Wingrad M, cotter S, Scheiman M. Anisometropic amblyopia: Is the patient ever too old to treat? Optom Vis Sci 1992;69:866-878. Isenberg S, Urist MJ. clinical observations in 101 consecutive patients with Duane's retraction syndrome. Am J Ophthalmol 1977;84:419-425. Brooks S, Johnson D, Fischer N. Anisometropia and Binocularity. Ophthalmology 1996;103:1139-1143. Benjamin WJ, Borish IM. Borish's clinical Refraction. Professional Press; 2006. p. 1479-1508. Schipper I. Anisophoria after implantation of an intraocular lens. J Am Intraocul Implant Soc 1985;11:290-291. Rosenbloom A, Morgan M. Principles and practice of pediatric optometry. Philadelphia: JB Lippincott; 1990. p. 243-251. Nelson L, calhoun J, Harley R. Pediatric ophthalmology, 3rd ed. WB Saunders; 1991. p. 222-234. Karimian F, Feizi S, Jafarinasab MR. conventional versus custom ablation in photorefractive keratectomy: Randomized clinical trial.