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Rosai-Dorfman Disease Presenting as Massive Mediastinal Lymphadenopathy in an Elderly Man

Publication ,  Journal Article
Maniar, YM; Meyer, CF; Sharp, M; Zambidis, ET; Qaysi, NAI; Horne, AJ
Published in: Annals of Internal Medicine Clinical Cases
October 1, 2022

We present a patient case of a 73-year-old man with new-onset substernal chest pain and B symptoms, found on computed tomography imaging to have massive mediastinal lymphadenopathy of more than 6 cm. Positron emission tomography imaging revealed fluorodeoxyglucose-avid nodes further extending to the axillary, abdominal, and inguinal regions. After a broad patient work-up for infectious, malignant, and rheumatic causes, he was ultimately diagnosed with Rosai-Dorfman disease, a rare histiocytic neoplasm, by excisional lymph node biopsy.

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Published In

Annals of Internal Medicine Clinical Cases

DOI

EISSN

2767-7664

Publication Date

October 1, 2022

Volume

1

Issue

8
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Maniar, Y. M., Meyer, C. F., Sharp, M., Zambidis, E. T., Qaysi, N. A. I., & Horne, A. J. (2022). Rosai-Dorfman Disease Presenting as Massive Mediastinal Lymphadenopathy in an Elderly Man. Annals of Internal Medicine Clinical Cases, 1(8). https://doi.org/10.7326/aimcc.2022.0539
Maniar, Y. M., C. F. Meyer, M. Sharp, E. T. Zambidis, N. A. I. Qaysi, and A. J. Horne. “Rosai-Dorfman Disease Presenting as Massive Mediastinal Lymphadenopathy in an Elderly Man.” Annals of Internal Medicine Clinical Cases 1, no. 8 (October 1, 2022). https://doi.org/10.7326/aimcc.2022.0539.
Maniar YM, Meyer CF, Sharp M, Zambidis ET, Qaysi NAI, Horne AJ. Rosai-Dorfman Disease Presenting as Massive Mediastinal Lymphadenopathy in an Elderly Man. Annals of Internal Medicine Clinical Cases. 2022 Oct 1;1(8).
Maniar, Y. M., et al. “Rosai-Dorfman Disease Presenting as Massive Mediastinal Lymphadenopathy in an Elderly Man.” Annals of Internal Medicine Clinical Cases, vol. 1, no. 8, Oct. 2022. Scopus, doi:10.7326/aimcc.2022.0539.
Maniar YM, Meyer CF, Sharp M, Zambidis ET, Qaysi NAI, Horne AJ. Rosai-Dorfman Disease Presenting as Massive Mediastinal Lymphadenopathy in an Elderly Man. Annals of Internal Medicine Clinical Cases. 2022 Oct 1;1(8).

Published In

Annals of Internal Medicine Clinical Cases

DOI

EISSN

2767-7664

Publication Date

October 1, 2022

Volume

1

Issue

8