Skip to main content
Journal cover image

High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts.

Publication ,  Journal Article
Cech, NB; Eleazer, MS; Shoffner, LT; Crosswhite, MR; Davis, AC; Mortenson, AM
Published in: J Chromatogr A
January 27, 2006

Extracts of the plant Echinacea purpurea are widely used for medicinal purposes. Effective quality control of these extracts requires rapid methods to determine their chemical composition. A new method for analysis of caffeic acid derivatives and alkamides from Echinacea extracts has been developed. With this method, isomeric isobutylamides and 2-methylbutylamides can be distinguished, a capability that previously published methods have lacked. Quantitative analyses carried out with this method on E. purpurea extracts that have been stored for 18 months indicate that they contain caftaric acid, cichoric acid, and undeca-2Z,4E-diene-8,10-diynoic acid isobutylamide at concentrations of 0.7, 0.71 and 2.0mg/mL, respectively.

Duke Scholars

Published In

J Chromatogr A

DOI

ISSN

0021-9673

Publication Date

January 27, 2006

Volume

1103

Issue

2

Start / End Page

219 / 228

Location

Netherlands

Related Subject Headings

  • Spectrometry, Mass, Electrospray Ionization
  • Plant Roots
  • Plant Extracts
  • Echinacea
  • Chromatography, High Pressure Liquid
  • Caffeic Acids
  • Analytical Chemistry
  • Amides
  • 40 Engineering
  • 34 Chemical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Cech, N. B., Eleazer, M. S., Shoffner, L. T., Crosswhite, M. R., Davis, A. C., & Mortenson, A. M. (2006). High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts. J Chromatogr A, 1103(2), 219–228. https://doi.org/10.1016/j.chroma.2005.11.008
Cech, Nadja B., Maqueita S. Eleazer, Lawresa T. Shoffner, Mark R. Crosswhite, Amanda C. Davis, and Ashley M. Mortenson. “High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts.J Chromatogr A 1103, no. 2 (January 27, 2006): 219–28. https://doi.org/10.1016/j.chroma.2005.11.008.
Cech, Nadja B., et al. “High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts.J Chromatogr A, vol. 1103, no. 2, Jan. 2006, pp. 219–28. Pubmed, doi:10.1016/j.chroma.2005.11.008.
Journal cover image

Published In

J Chromatogr A

DOI

ISSN

0021-9673

Publication Date

January 27, 2006

Volume

1103

Issue

2

Start / End Page

219 / 228

Location

Netherlands

Related Subject Headings

  • Spectrometry, Mass, Electrospray Ionization
  • Plant Roots
  • Plant Extracts
  • Echinacea
  • Chromatography, High Pressure Liquid
  • Caffeic Acids
  • Analytical Chemistry
  • Amides
  • 40 Engineering
  • 34 Chemical sciences