High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts.
Publication
, Journal Article
Cech, NB; Eleazer, MS; Shoffner, LT; Crosswhite, MR; Davis, AC; Mortenson, AM
Published in: J Chromatogr A
January 27, 2006
Extracts of the plant Echinacea purpurea are widely used for medicinal purposes. Effective quality control of these extracts requires rapid methods to determine their chemical composition. A new method for analysis of caffeic acid derivatives and alkamides from Echinacea extracts has been developed. With this method, isomeric isobutylamides and 2-methylbutylamides can be distinguished, a capability that previously published methods have lacked. Quantitative analyses carried out with this method on E. purpurea extracts that have been stored for 18 months indicate that they contain caftaric acid, cichoric acid, and undeca-2Z,4E-diene-8,10-diynoic acid isobutylamide at concentrations of 0.7, 0.71 and 2.0mg/mL, respectively.
Duke Scholars
Published In
J Chromatogr A
DOI
ISSN
0021-9673
Publication Date
January 27, 2006
Volume
1103
Issue
2
Start / End Page
219 / 228
Location
Netherlands
Related Subject Headings
- Spectrometry, Mass, Electrospray Ionization
- Plant Roots
- Plant Extracts
- Echinacea
- Chromatography, High Pressure Liquid
- Caffeic Acids
- Analytical Chemistry
- Amides
- 40 Engineering
- 34 Chemical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Cech, N. B., Eleazer, M. S., Shoffner, L. T., Crosswhite, M. R., Davis, A. C., & Mortenson, A. M. (2006). High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts. J Chromatogr A, 1103(2), 219–228. https://doi.org/10.1016/j.chroma.2005.11.008
Cech, Nadja B., Maqueita S. Eleazer, Lawresa T. Shoffner, Mark R. Crosswhite, Amanda C. Davis, and Ashley M. Mortenson. “High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts.” J Chromatogr A 1103, no. 2 (January 27, 2006): 219–28. https://doi.org/10.1016/j.chroma.2005.11.008.
Cech NB, Eleazer MS, Shoffner LT, Crosswhite MR, Davis AC, Mortenson AM. High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts. J Chromatogr A. 2006 Jan 27;1103(2):219–28.
Cech, Nadja B., et al. “High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts.” J Chromatogr A, vol. 1103, no. 2, Jan. 2006, pp. 219–28. Pubmed, doi:10.1016/j.chroma.2005.11.008.
Cech NB, Eleazer MS, Shoffner LT, Crosswhite MR, Davis AC, Mortenson AM. High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts. J Chromatogr A. 2006 Jan 27;1103(2):219–228.
Published In
J Chromatogr A
DOI
ISSN
0021-9673
Publication Date
January 27, 2006
Volume
1103
Issue
2
Start / End Page
219 / 228
Location
Netherlands
Related Subject Headings
- Spectrometry, Mass, Electrospray Ionization
- Plant Roots
- Plant Extracts
- Echinacea
- Chromatography, High Pressure Liquid
- Caffeic Acids
- Analytical Chemistry
- Amides
- 40 Engineering
- 34 Chemical sciences