Solution NMR studies of the plant peptide hormone CEP inform function.
Publication
, Journal Article
Bobay, BG; DiGennaro, P; Scholl, E; Imin, N; Djordjevic, MA; Mck Bird, D
Published in: FEBS letters
December 2013
The C-terminally Encoded Peptide (CEP) family of regulatory peptides controls root development in vascular plants. Here, we present the first NMR structures of CEP. We show that root-knot nematode (RKN: Meloidogyne spp.) also encodes CEP, presumably to mimic plant CEP as part of their stereotypic, parasitic interaction with vascular plants. Molecular dynamics simulations of plant- and nematode-encoded CEP displaying known posttranslational modifications (PTM) provided insight into the structural effects of PTM and the conformational plasticity and rigidity of CEP. Potential mechanisms of action are discussed with respect to the structure and sampling of conformational space.
Duke Scholars
Published In
FEBS letters
DOI
EISSN
1873-3468
ISSN
0014-5793
Publication Date
December 2013
Volume
587
Issue
24
Start / End Page
3979 / 3985
Related Subject Headings
- Tylenchoidea
- Sequence Homology, Amino Acid
- Root Nodules, Plant
- Plants
- Plant Growth Regulators
- Plant Diseases
- Nuclear Magnetic Resonance, Biomolecular
- Molecular Sequence Data
- Molecular Mimicry
- Molecular Dynamics Simulation
Citation
APA
Chicago
ICMJE
MLA
NLM
Bobay, B. G., DiGennaro, P., Scholl, E., Imin, N., Djordjevic, M. A., & Mck Bird, D. (2013). Solution NMR studies of the plant peptide hormone CEP inform function. FEBS Letters, 587(24), 3979–3985. https://doi.org/10.1016/j.febslet.2013.10.033
Bobay, Benjamin G., Peter DiGennaro, Elizabeth Scholl, Nijat Imin, Michael A. Djordjevic, and David Mck Bird. “Solution NMR studies of the plant peptide hormone CEP inform function.” FEBS Letters 587, no. 24 (December 2013): 3979–85. https://doi.org/10.1016/j.febslet.2013.10.033.
Bobay BG, DiGennaro P, Scholl E, Imin N, Djordjevic MA, Mck Bird D. Solution NMR studies of the plant peptide hormone CEP inform function. FEBS letters. 2013 Dec;587(24):3979–85.
Bobay, Benjamin G., et al. “Solution NMR studies of the plant peptide hormone CEP inform function.” FEBS Letters, vol. 587, no. 24, Dec. 2013, pp. 3979–85. Epmc, doi:10.1016/j.febslet.2013.10.033.
Bobay BG, DiGennaro P, Scholl E, Imin N, Djordjevic MA, Mck Bird D. Solution NMR studies of the plant peptide hormone CEP inform function. FEBS letters. 2013 Dec;587(24):3979–3985.
Published In
FEBS letters
DOI
EISSN
1873-3468
ISSN
0014-5793
Publication Date
December 2013
Volume
587
Issue
24
Start / End Page
3979 / 3985
Related Subject Headings
- Tylenchoidea
- Sequence Homology, Amino Acid
- Root Nodules, Plant
- Plants
- Plant Growth Regulators
- Plant Diseases
- Nuclear Magnetic Resonance, Biomolecular
- Molecular Sequence Data
- Molecular Mimicry
- Molecular Dynamics Simulation