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Targeting RNA with cysteine-constrained peptides.

Publication ,  Journal Article
Burns, VA; Bobay, BG; Basso, A; Cavanagh, J; Melander, C
Published in: Bioorganic & medicinal chemistry letters
January 2008

A combined approach for targeting RNA with novel, biologically active ligands has been developed using a cyclic peptide library and in silico modeling. This approach has successfully identified novel cyclic peptide constructs that can target bTAR RNA. Subsequently, RNA/peptide interactions were effectively modeled using the HADDOCK docking program.

Duke Scholars

Published In

Bioorganic & medicinal chemistry letters

DOI

EISSN

1464-3405

ISSN

0960-894X

Publication Date

January 2008

Volume

18

Issue

2

Start / End Page

565 / 567

Related Subject Headings

  • RNA
  • Peptides, Cyclic
  • Models, Molecular
  • Medicinal & Biomolecular Chemistry
  • Humans
  • Cysteine
  • Base Sequence
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 1115 Pharmacology and Pharmaceutical Sciences
 

Citation

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ICMJE
MLA
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Burns, V. A., Bobay, B. G., Basso, A., Cavanagh, J., & Melander, C. (2008). Targeting RNA with cysteine-constrained peptides. Bioorganic & Medicinal Chemistry Letters, 18(2), 565–567. https://doi.org/10.1016/j.bmcl.2007.11.096
Burns, Virginia A., Benjamin G. Bobay, Anne Basso, John Cavanagh, and Christian Melander. “Targeting RNA with cysteine-constrained peptides.Bioorganic & Medicinal Chemistry Letters 18, no. 2 (January 2008): 565–67. https://doi.org/10.1016/j.bmcl.2007.11.096.
Burns VA, Bobay BG, Basso A, Cavanagh J, Melander C. Targeting RNA with cysteine-constrained peptides. Bioorganic & medicinal chemistry letters. 2008 Jan;18(2):565–7.
Burns, Virginia A., et al. “Targeting RNA with cysteine-constrained peptides.Bioorganic & Medicinal Chemistry Letters, vol. 18, no. 2, Jan. 2008, pp. 565–67. Epmc, doi:10.1016/j.bmcl.2007.11.096.
Burns VA, Bobay BG, Basso A, Cavanagh J, Melander C. Targeting RNA with cysteine-constrained peptides. Bioorganic & medicinal chemistry letters. 2008 Jan;18(2):565–567.
Journal cover image

Published In

Bioorganic & medicinal chemistry letters

DOI

EISSN

1464-3405

ISSN

0960-894X

Publication Date

January 2008

Volume

18

Issue

2

Start / End Page

565 / 567

Related Subject Headings

  • RNA
  • Peptides, Cyclic
  • Models, Molecular
  • Medicinal & Biomolecular Chemistry
  • Humans
  • Cysteine
  • Base Sequence
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 1115 Pharmacology and Pharmaceutical Sciences