Targeting RNA with cysteine-constrained peptides.
Publication
, Journal Article
Burns, VA; Bobay, BG; Basso, A; Cavanagh, J; Melander, C
Published in: Bioorg Med Chem Lett
January 15, 2008
A combined approach for targeting RNA with novel, biologically active ligands has been developed using a cyclic peptide library and in silico modeling. This approach has successfully identified novel cyclic peptide constructs that can target bTAR RNA. Subsequently, RNA/peptide interactions were effectively modeled using the HADDOCK docking program.
Duke Scholars
Published In
Bioorg Med Chem Lett
DOI
EISSN
1464-3405
Publication Date
January 15, 2008
Volume
18
Issue
2
Start / End Page
565 / 567
Location
England
Related Subject Headings
- RNA
- Peptides, Cyclic
- Models, Molecular
- Medicinal & Biomolecular Chemistry
- Humans
- Cysteine
- Base Sequence
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 1115 Pharmacology and Pharmaceutical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Burns, V. A., Bobay, B. G., Basso, A., Cavanagh, J., & Melander, C. (2008). Targeting RNA with cysteine-constrained peptides. Bioorg Med Chem Lett, 18(2), 565–567. https://doi.org/10.1016/j.bmcl.2007.11.096
Burns, Virginia A., Benjamin G. Bobay, Anne Basso, John Cavanagh, and Christian Melander. “Targeting RNA with cysteine-constrained peptides.” Bioorg Med Chem Lett 18, no. 2 (January 15, 2008): 565–67. https://doi.org/10.1016/j.bmcl.2007.11.096.
Burns VA, Bobay BG, Basso A, Cavanagh J, Melander C. Targeting RNA with cysteine-constrained peptides. Bioorg Med Chem Lett. 2008 Jan 15;18(2):565–7.
Burns, Virginia A., et al. “Targeting RNA with cysteine-constrained peptides.” Bioorg Med Chem Lett, vol. 18, no. 2, Jan. 2008, pp. 565–67. Pubmed, doi:10.1016/j.bmcl.2007.11.096.
Burns VA, Bobay BG, Basso A, Cavanagh J, Melander C. Targeting RNA with cysteine-constrained peptides. Bioorg Med Chem Lett. 2008 Jan 15;18(2):565–567.
Published In
Bioorg Med Chem Lett
DOI
EISSN
1464-3405
Publication Date
January 15, 2008
Volume
18
Issue
2
Start / End Page
565 / 567
Location
England
Related Subject Headings
- RNA
- Peptides, Cyclic
- Models, Molecular
- Medicinal & Biomolecular Chemistry
- Humans
- Cysteine
- Base Sequence
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 1115 Pharmacology and Pharmaceutical Sciences