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Identifying subtypes of HIV/AIDS-related symptoms in China using latent profile analysis and symptom networks.

Publication ,  Journal Article
Yang, Z; Zhu, Z; Wen, H; Han, S; Zhang, L; Fu, Y; Hu, Y; Wu, B
Published in: Scientific reports
August 2022

The identification of subgroups of people living with HIV in China based on the severity of symptom clusters and individual symptoms is crucial to determine group-specific symptom management strategies. Participants reported 27 highly prevalent HIV/AIDS-related symptoms. Latent profile analysis based on symptom severity was used to identify person-centered subtypes of HIV/AIDS-related symptoms. Symptom networks were compared among subgroups identified by latent profile analysis. A total of 2927 eligible people living with HIV (PWH) were included in the analysis. Five profiles were identified: "Profile 1: all low symptom severity" (n2 = 2094, 71.54%), "Profile 2: medium symptom severity with syndemic conditions" (n3 = 109, 3.72%), "Profile 3: medium symptom severity with low functional status" (n1 = 165, 5.64%), "Profile 4: medium symptom severity in transitional period" (n4 = 448, 15.31%), and "Profile 5: all high symptom severity" (n5 = 111, 3.79%). Except for Profile 1 and Profile 5, the symptom severity was similar among the other three profiles. Profiles 1 (2.09 ± 0.52) and 4 (2.44 ± 0.66) had the smallest ∑s values, and Profiles 2 (4.38 ± 1.40) and 5 (4.39 ± 1.22) had the largest ∑s values. Our study demonstrates the need for health care professionals to provide PWH with group-specific symptom management interventions based on five profiles to improve their physical and psychological well-being. Future studies should be conducted in different contexts using different symptom checklists to further validate our results.

Duke Scholars

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Published In

Scientific reports

DOI

EISSN

2045-2322

ISSN

2045-2322

Publication Date

August 2022

Volume

12

Issue

1

Start / End Page

13271

Related Subject Headings

  • Palliative Care
  • Humans
  • China
  • Acquired Immunodeficiency Syndrome
 

Citation

APA
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MLA
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Yang, Z., Zhu, Z., Wen, H., Han, S., Zhang, L., Fu, Y., … Wu, B. (2022). Identifying subtypes of HIV/AIDS-related symptoms in China using latent profile analysis and symptom networks. Scientific Reports, 12(1), 13271. https://doi.org/10.1038/s41598-022-17720-z
Yang, Zhongfang, Zheng Zhu, Huan Wen, Shuyu Han, Lin Zhang, Yanfen Fu, Yan Hu, and Bei Wu. “Identifying subtypes of HIV/AIDS-related symptoms in China using latent profile analysis and symptom networks.Scientific Reports 12, no. 1 (August 2022): 13271. https://doi.org/10.1038/s41598-022-17720-z.
Yang Z, Zhu Z, Wen H, Han S, Zhang L, Fu Y, et al. Identifying subtypes of HIV/AIDS-related symptoms in China using latent profile analysis and symptom networks. Scientific reports. 2022 Aug;12(1):13271.
Yang, Zhongfang, et al. “Identifying subtypes of HIV/AIDS-related symptoms in China using latent profile analysis and symptom networks.Scientific Reports, vol. 12, no. 1, Aug. 2022, p. 13271. Epmc, doi:10.1038/s41598-022-17720-z.
Yang Z, Zhu Z, Wen H, Han S, Zhang L, Fu Y, Hu Y, Wu B. Identifying subtypes of HIV/AIDS-related symptoms in China using latent profile analysis and symptom networks. Scientific reports. 2022 Aug;12(1):13271.

Published In

Scientific reports

DOI

EISSN

2045-2322

ISSN

2045-2322

Publication Date

August 2022

Volume

12

Issue

1

Start / End Page

13271

Related Subject Headings

  • Palliative Care
  • Humans
  • China
  • Acquired Immunodeficiency Syndrome