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Partial Component Exchange of a Non-Infected Inflatable Penile Prosthesis is Associated With a Higher Complication Rate.

Publication ,  Journal Article
Barham, DW; Choi, E; Hammad, M; Swerdloff, D; Berk, BD; Chung, E; Clavell-Hernandez, J; Gross, MS; Jenkins, LC; Jones, JM; Kathrins, MN ...
Published in: Urology
April 2023

OBJECTIVE: To describe the infectious and non-infectious complications in men undergoing Inflatable penile prosthesis (IPP) revision with partial and complete component exchange for mechanical malfunction. METHODS: We performed a multicenter retrospective cohort study of patients who underwent IPP revision. Men undergoing procedures for implant infection were excluded. Patients were divided into those who had complete exchange of the entire device or partial exchange of only one or 2 components. Infectious and non-infectious complications were compared between groups. RESULTS: Three hundred sixty-eight men had complete exchange of the entire device and 85 had partial component exchange. Men undergoing partial exchange had a significantly higher infection rate (7.1% vs 2.2%, P = .031). The partial exchange group also was more likely to receive antifungals (51.8 vs 16.6%, P < .001), have a modified salvage washout (77.4 vs 60.2%, P = .004), and less likely to receive vancomycin and gentamicin (63.5 vs 83.7%, P < .001). Time to revision was significantly shorter in the partial exchange group (44.9 vs 168.2 months, P < .001). Mean follow-up was slightly longer in the complete exchange group (18.3 vs 13.0 months). In multivariable analysis, partial exchange surgery, vancomycin and gentamicin prophylaxis, modified salvage washout, and antifungal prophylaxis were no longer associated with postoperative infections. The partial exchange group had greater rates of non-infectious complications (21.2% vs 9.5%, P = .005) such as pump malfunction and tubing breakage. CONCLUSION: Patients undergoing partial component revision had more infectious and non-infectious complications. These findings suggest that partial component exchange increases complications in men undergoing IPP revision.

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Published In

Urology

DOI

EISSN

1527-9995

Publication Date

April 2023

Volume

174

Start / End Page

128 / 134

Location

United States

Related Subject Headings

  • Vancomycin
  • Urology & Nephrology
  • Retrospective Studies
  • Postoperative Complications
  • Penile Prosthesis
  • Penile Implantation
  • Male
  • Humans
  • Gentamicins
  • Erectile Dysfunction
 

Citation

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Chicago
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MLA
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Barham, D. W., Choi, E., Hammad, M., Swerdloff, D., Berk, B. D., Chung, E., … Yafi, F. A. (2023). Partial Component Exchange of a Non-Infected Inflatable Penile Prosthesis is Associated With a Higher Complication Rate. Urology, 174, 128–134. https://doi.org/10.1016/j.urology.2022.11.050
Barham, David W., Edward Choi, Muhammed Hammad, Daniel Swerdloff, Brittany D. Berk, Eric Chung, Jonathan Clavell-Hernandez, et al. “Partial Component Exchange of a Non-Infected Inflatable Penile Prosthesis is Associated With a Higher Complication Rate.Urology 174 (April 2023): 128–34. https://doi.org/10.1016/j.urology.2022.11.050.
Barham DW, Choi E, Hammad M, Swerdloff D, Berk BD, Chung E, et al. Partial Component Exchange of a Non-Infected Inflatable Penile Prosthesis is Associated With a Higher Complication Rate. Urology. 2023 Apr;174:128–34.
Barham, David W., et al. “Partial Component Exchange of a Non-Infected Inflatable Penile Prosthesis is Associated With a Higher Complication Rate.Urology, vol. 174, Apr. 2023, pp. 128–34. Pubmed, doi:10.1016/j.urology.2022.11.050.
Barham DW, Choi E, Hammad M, Swerdloff D, Berk BD, Chung E, Clavell-Hernandez J, Gross MS, Jenkins LC, Jones JM, Kathrins MN, Lentz AC, Schammel J, Selph JP, Simhan J, Welliver C, Yafi FA. Partial Component Exchange of a Non-Infected Inflatable Penile Prosthesis is Associated With a Higher Complication Rate. Urology. 2023 Apr;174:128–134.
Journal cover image

Published In

Urology

DOI

EISSN

1527-9995

Publication Date

April 2023

Volume

174

Start / End Page

128 / 134

Location

United States

Related Subject Headings

  • Vancomycin
  • Urology & Nephrology
  • Retrospective Studies
  • Postoperative Complications
  • Penile Prosthesis
  • Penile Implantation
  • Male
  • Humans
  • Gentamicins
  • Erectile Dysfunction