Skip to main content
Journal cover image

Intravascular Ultrasound-Guided Transvenous Biopsy of Retroperitoneal Lymph Nodes: Diagnostic Accuracy and Safety Compared with CT-Guided Percutaneous Biopsy.

Publication ,  Journal Article
Buchholz, J; Cline, BC; Martin, JG; Kim, CY; Ronald, J
Published in: J Vasc Interv Radiol
April 2023

PURPOSE: To compare the diagnostic accuracy and adverse event rates of intravascular ultrasound (US)-guided transvenous biopsy (TVB) versus those of computed tomography (CT)-guided percutaneous needle biopsy (PNB) for retroperitoneal (RP) lymph nodes. MATERIALS AND METHODS: In this single-institution, retrospective study, 32 intravascular US-guided TVB procedures and a sample of 34 CT-guided PNB procedures for RP lymph nodes where targets were deemed amenable to intravascular US-guided TVB were analyzed. Procedural metrics, including diagnostic accuracy, defined as diagnostic of malignancy or a clinically verifiable benign result, and adverse event rates were compared. RESULTS: The targets of intravascular US-guided TVB were primarily aortocaval (47%, 15/32) or precaval (34%, 11/32), whereas those of CT-guided PNB were primarily right pericaval (44%, 15/34) or retrocaval (44%, 15/34) (P < .001). The targets of intravascular US-guided TVB averaged 2.4 cm in the long axis (range, 1.3-3.7 cm) compared with 2.9 cm (range, 1.4-5.7 cm) for those of CT-guided PNB (P = .02). There was no difference in the average number of needle passes (3.8 for intravascular US-guided TVB vs 3.9 for CT-guided PNB; P = .68). The diagnostic accuracy was 94% (30/32) and the adverse event rate was 3.1% (1/32) for intravascular US-guided TVB, similar to those of CT-guided PNB (accuracy, 91% [31/34]; adverse event rate, 2.9% [1/34]). CONCLUSIONS: Intravascular US-guided TVB had a diagnostic accuracy and adverse event rate similar to CT-guided PNB for RP lymph nodes, indicating that intravascular US-guided TVB may be as safe and effective as conventional biopsy approaches for appropriately selected targets.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J Vasc Interv Radiol

DOI

EISSN

1535-7732

Publication Date

April 2023

Volume

34

Issue

4

Start / End Page

710 / 715

Location

United States

Related Subject Headings

  • Ultrasonography, Interventional
  • Tomography, X-Ray Computed
  • Retrospective Studies
  • Nuclear Medicine & Medical Imaging
  • Lymph Nodes
  • Image-Guided Biopsy
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Buchholz, J., Cline, B. C., Martin, J. G., Kim, C. Y., & Ronald, J. (2023). Intravascular Ultrasound-Guided Transvenous Biopsy of Retroperitoneal Lymph Nodes: Diagnostic Accuracy and Safety Compared with CT-Guided Percutaneous Biopsy. J Vasc Interv Radiol, 34(4), 710–715. https://doi.org/10.1016/j.jvir.2022.12.479
Buchholz, Joseph, Brendan C. Cline, Jonathan G. Martin, Charles Y. Kim, and James Ronald. “Intravascular Ultrasound-Guided Transvenous Biopsy of Retroperitoneal Lymph Nodes: Diagnostic Accuracy and Safety Compared with CT-Guided Percutaneous Biopsy.J Vasc Interv Radiol 34, no. 4 (April 2023): 710–15. https://doi.org/10.1016/j.jvir.2022.12.479.
Buchholz, Joseph, et al. “Intravascular Ultrasound-Guided Transvenous Biopsy of Retroperitoneal Lymph Nodes: Diagnostic Accuracy and Safety Compared with CT-Guided Percutaneous Biopsy.J Vasc Interv Radiol, vol. 34, no. 4, Apr. 2023, pp. 710–15. Pubmed, doi:10.1016/j.jvir.2022.12.479.
Journal cover image

Published In

J Vasc Interv Radiol

DOI

EISSN

1535-7732

Publication Date

April 2023

Volume

34

Issue

4

Start / End Page

710 / 715

Location

United States

Related Subject Headings

  • Ultrasonography, Interventional
  • Tomography, X-Ray Computed
  • Retrospective Studies
  • Nuclear Medicine & Medical Imaging
  • Lymph Nodes
  • Image-Guided Biopsy
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences