How to manage coagulopathies in critically ill patients.
Publication
, Journal Article
Helms, J; Iba, T; Connors, JM; Gando, S; Levi, M; Meziani, F; Levy, JH
Published in: Intensive Care Med
March 2023
Coagulopathy is a severe and frequent complication in critically ill patients, for which the pathogenesis and presentation may be variable depending on the underlying disease. Based on the dominant clinical phenotype, the current review differentiates between hemorrhagic coagulopathies, characterized by a hypocoagulable and hyperfibrinolysis state, and thrombotic coagulopathies with a systemic prothrombotic and antifibrinolytic phenotype. We discuss the differences in pathogenesis and treatment of the common coagulopathies.
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Published In
Intensive Care Med
DOI
EISSN
1432-1238
Publication Date
March 2023
Volume
49
Issue
3
Start / End Page
273 / 290
Location
United States
Related Subject Headings
- Thrombosis
- Phenotype
- Humans
- Emergency & Critical Care Medicine
- Disseminated Intravascular Coagulation
- Critical Illness
- Blood Coagulation Disorders
- 3202 Clinical sciences
- 1117 Public Health and Health Services
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Helms, J., Iba, T., Connors, J. M., Gando, S., Levi, M., Meziani, F., & Levy, J. H. (2023). How to manage coagulopathies in critically ill patients. Intensive Care Med, 49(3), 273–290. https://doi.org/10.1007/s00134-023-06980-6
Helms, Julie, Toshiaki Iba, Jean Marie Connors, Satoshi Gando, Marcel Levi, Ferhat Meziani, and Jerrold H. Levy. “How to manage coagulopathies in critically ill patients.” Intensive Care Med 49, no. 3 (March 2023): 273–90. https://doi.org/10.1007/s00134-023-06980-6.
Helms J, Iba T, Connors JM, Gando S, Levi M, Meziani F, et al. How to manage coagulopathies in critically ill patients. Intensive Care Med. 2023 Mar;49(3):273–90.
Helms, Julie, et al. “How to manage coagulopathies in critically ill patients.” Intensive Care Med, vol. 49, no. 3, Mar. 2023, pp. 273–90. Pubmed, doi:10.1007/s00134-023-06980-6.
Helms J, Iba T, Connors JM, Gando S, Levi M, Meziani F, Levy JH. How to manage coagulopathies in critically ill patients. Intensive Care Med. 2023 Mar;49(3):273–290.
Published In
Intensive Care Med
DOI
EISSN
1432-1238
Publication Date
March 2023
Volume
49
Issue
3
Start / End Page
273 / 290
Location
United States
Related Subject Headings
- Thrombosis
- Phenotype
- Humans
- Emergency & Critical Care Medicine
- Disseminated Intravascular Coagulation
- Critical Illness
- Blood Coagulation Disorders
- 3202 Clinical sciences
- 1117 Public Health and Health Services
- 1103 Clinical Sciences