
Brassinosteroid gene regulatory networks at cellular resolution in the Arabidopsis root.
Brassinosteroids are plant steroid hormones that regulate diverse processes, such as cell division and cell elongation, through gene regulatory networks that vary in space and time. By using time series single-cell RNA sequencing to profile brassinosteroid-responsive gene expression specific to different cell types and developmental stages of the Arabidopsis root, we identified the elongating cortex as a site where brassinosteroids trigger a shift from proliferation to elongation associated with increased expression of cell wall-related genes. Our analysis revealed HOMEOBOX FROM ARABIDOPSIS THALIANA 7 (HAT7) and GT-2-LIKE 1 (GTL1) as brassinosteroid-responsive transcription factors that regulate cortex cell elongation. These results establish the cortex as a site of brassinosteroid-mediated growth and unveil a brassinosteroid signaling network regulating the transition from proliferation to elongation, which illuminates aspects of spatiotemporal hormone responses.
Duke Scholars
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Related Subject Headings
- Transcription Factors
- Plant Roots
- Plant Growth Regulators
- Homeodomain Proteins
- General Science & Technology
- Gene Regulatory Networks
- Gene Expression Regulation, Plant
- Cell Division
- Cell Differentiation
- Brassinosteroids
Citation

Published In
DOI
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Transcription Factors
- Plant Roots
- Plant Growth Regulators
- Homeodomain Proteins
- General Science & Technology
- Gene Regulatory Networks
- Gene Expression Regulation, Plant
- Cell Division
- Cell Differentiation
- Brassinosteroids