
Congenital cystic hemangioblastomas of the cerebral hemisphere in a neonate without alteration in the VHL gene.
Publication
, Journal Article
Johnson, MD; Mitchell, AR; Troup, EC; Bhowmick, DA; Wait, SD; Aulino, J; Zhuang, Z; Weil, RJ
Published in: Pediatr Neurosurg
2004
A 4-week-old child presented with lethargy, emesis, decreased spontaneous movements, and a bulging fontanelle. Neuroimaging demonstrated a large, hemispheric, multicystic lesion with multiple enhancing nodules, which, on pathological examination, proved to be multiple, distinct hemangioblastomas. Careful molecular analysis failed to reveal alterations of the VHL gene. This represents an uncommon presentation for these tumors and suggests that genes other than VHL may be important in the genesis of these tumors.
Duke Scholars
Published In
Pediatr Neurosurg
DOI
ISSN
1016-2291
Publication Date
2004
Volume
40
Issue
3
Start / End Page
124 / 127
Location
Switzerland
Related Subject Headings
- Von Hippel-Lindau Tumor Suppressor Protein
- Ubiquitin-Protein Ligases
- Tumor Suppressor Proteins
- Supratentorial Neoplasms
- Neurology & Neurosurgery
- Male
- Infant, Newborn
- Humans
- Hemangioblastoma
- 3213 Paediatrics
Citation
APA
Chicago
ICMJE
MLA
NLM
Johnson, M. D., Mitchell, A. R., Troup, E. C., Bhowmick, D. A., Wait, S. D., Aulino, J., … Weil, R. J. (2004). Congenital cystic hemangioblastomas of the cerebral hemisphere in a neonate without alteration in the VHL gene. Pediatr Neurosurg, 40(3), 124–127. https://doi.org/10.1159/000079854
Johnson, Mahlon D., Alex R. Mitchell, E Christopher Troup, Deb A. Bhowmick, Scott D. Wait, Joseph Aulino, Zhengping Zhuang, and Robert J. Weil. “Congenital cystic hemangioblastomas of the cerebral hemisphere in a neonate without alteration in the VHL gene.” Pediatr Neurosurg 40, no. 3 (2004): 124–27. https://doi.org/10.1159/000079854.
Johnson MD, Mitchell AR, Troup EC, Bhowmick DA, Wait SD, Aulino J, et al. Congenital cystic hemangioblastomas of the cerebral hemisphere in a neonate without alteration in the VHL gene. Pediatr Neurosurg. 2004;40(3):124–7.
Johnson, Mahlon D., et al. “Congenital cystic hemangioblastomas of the cerebral hemisphere in a neonate without alteration in the VHL gene.” Pediatr Neurosurg, vol. 40, no. 3, 2004, pp. 124–27. Pubmed, doi:10.1159/000079854.
Johnson MD, Mitchell AR, Troup EC, Bhowmick DA, Wait SD, Aulino J, Zhuang Z, Weil RJ. Congenital cystic hemangioblastomas of the cerebral hemisphere in a neonate without alteration in the VHL gene. Pediatr Neurosurg. 2004;40(3):124–127.

Published In
Pediatr Neurosurg
DOI
ISSN
1016-2291
Publication Date
2004
Volume
40
Issue
3
Start / End Page
124 / 127
Location
Switzerland
Related Subject Headings
- Von Hippel-Lindau Tumor Suppressor Protein
- Ubiquitin-Protein Ligases
- Tumor Suppressor Proteins
- Supratentorial Neoplasms
- Neurology & Neurosurgery
- Male
- Infant, Newborn
- Humans
- Hemangioblastoma
- 3213 Paediatrics