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Tumor hormone receptor status and recurrences in premenopausal patients with node-negative breast carcinoma.

Publication ,  Journal Article
Tsangaris, TN; Knox, SM; Cheek, JH
Published in: Cancer
February 15, 1992

To ascertain the prognostic significance of tumor hormone receptor status in premenopausal patients with node-negative breast cancer, a retrospective review of 199 patients who met these criteria was conducted. Of these 199 patients, estrogen receptor (ER) data were available for 147. One hundred four patients (71%) had ER-negative disease and 22 (21%) exhibited local or distant recurrence with a median follow-up time of 85.4 months. Thirteen patients in this group had died of breast cancer. Of the 43 patients who had ER-positive disease, 5 (12%) had recurrences and 2 died of breast cancer. After observing patients for a longer period of time (median follow-up time, 85.4 months), no statistically significant differences in disease-free survival (DFS) or overall survival (OS) were demonstrated. However, as seen in our first analysis of this group at 45 months, tumor size after a median follow-up time of 85.4 months continues to have significant prognostic implications, regardless of ER status.

Duke Scholars

Published In

Cancer

DOI

ISSN

0008-543X

Publication Date

February 15, 1992

Volume

69

Issue

4

Start / End Page

984 / 987

Location

United States

Related Subject Headings

  • Survival Analysis
  • Retrospective Studies
  • Receptors, Progesterone
  • Receptors, Estrogen
  • Prognosis
  • Oncology & Carcinogenesis
  • Middle Aged
  • Menopause
  • Mastectomy, Simple
  • Mastectomy, Segmental
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Tsangaris, T. N., Knox, S. M., & Cheek, J. H. (1992). Tumor hormone receptor status and recurrences in premenopausal patients with node-negative breast carcinoma. Cancer, 69(4), 984–987. https://doi.org/10.1002/1097-0142(19920215)69:4<984::aid-cncr2820690425>3.0.co;2-c
Tsangaris, T. N., S. M. Knox, and J. H. Cheek. “Tumor hormone receptor status and recurrences in premenopausal patients with node-negative breast carcinoma.Cancer 69, no. 4 (February 15, 1992): 984–87. https://doi.org/10.1002/1097-0142(19920215)69:4<984::aid-cncr2820690425>3.0.co;2-c.
Tsangaris, T. N., et al. “Tumor hormone receptor status and recurrences in premenopausal patients with node-negative breast carcinoma.Cancer, vol. 69, no. 4, Feb. 1992, pp. 984–87. Pubmed, doi:10.1002/1097-0142(19920215)69:4<984::aid-cncr2820690425>3.0.co;2-c.
Journal cover image

Published In

Cancer

DOI

ISSN

0008-543X

Publication Date

February 15, 1992

Volume

69

Issue

4

Start / End Page

984 / 987

Location

United States

Related Subject Headings

  • Survival Analysis
  • Retrospective Studies
  • Receptors, Progesterone
  • Receptors, Estrogen
  • Prognosis
  • Oncology & Carcinogenesis
  • Middle Aged
  • Menopause
  • Mastectomy, Simple
  • Mastectomy, Segmental