Growing Heart Valve Implants for Children.
Publication
, Journal Article
Konsek, H; Sherard, C; Bisbee, C; Kang, L; Turek, JW; Rajab, TK
Published in: J Cardiovasc Dev Dis
March 31, 2023
The current standard of care for pediatric patients with unrepairable congenital valvular disease is a heart valve implant. However, current heart valve implants are unable to accommodate the somatic growth of the recipient, preventing long-term clinical success in these patients. Therefore, there is an urgent need for a growing heart valve implant for children. This article reviews recent studies investigating tissue-engineered heart valves and partial heart transplantation as potential growing heart valve implants in large animal and clinical translational research. In vitro and in situ designs of tissue engineered heart valves are discussed, as well as the barriers to clinical translation.
Duke Scholars
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Published In
J Cardiovasc Dev Dis
DOI
EISSN
2308-3425
Publication Date
March 31, 2023
Volume
10
Issue
4
Location
Switzerland
Related Subject Headings
- 3201 Cardiovascular medicine and haematology
Citation
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Konsek, H., Sherard, C., Bisbee, C., Kang, L., Turek, J. W., & Rajab, T. K. (2023). Growing Heart Valve Implants for Children. J Cardiovasc Dev Dis, 10(4). https://doi.org/10.3390/jcdd10040148
Konsek, Haley, Curry Sherard, Cora Bisbee, Lillian Kang, Joseph W. Turek, and Taufiek K. Rajab. “Growing Heart Valve Implants for Children.” J Cardiovasc Dev Dis 10, no. 4 (March 31, 2023). https://doi.org/10.3390/jcdd10040148.
Konsek H, Sherard C, Bisbee C, Kang L, Turek JW, Rajab TK. Growing Heart Valve Implants for Children. J Cardiovasc Dev Dis. 2023 Mar 31;10(4).
Konsek, Haley, et al. “Growing Heart Valve Implants for Children.” J Cardiovasc Dev Dis, vol. 10, no. 4, Mar. 2023. Pubmed, doi:10.3390/jcdd10040148.
Konsek H, Sherard C, Bisbee C, Kang L, Turek JW, Rajab TK. Growing Heart Valve Implants for Children. J Cardiovasc Dev Dis. 2023 Mar 31;10(4).
Published In
J Cardiovasc Dev Dis
DOI
EISSN
2308-3425
Publication Date
March 31, 2023
Volume
10
Issue
4
Location
Switzerland
Related Subject Headings
- 3201 Cardiovascular medicine and haematology