Responder Analyses: A Methodological Mess.
Publication
, Journal Article
Cook, CE; Bejarano, G; Reneker, J; Vigotsky, AD; Riddle, DL
Published in: J Orthop Sports Phys Ther
November 2023
SYNOPSIS: Responder analyses are methods for analyzing randomized controlled trials, which purport to identify individuals or subgroups of study participants who experienced a "clinically meaningful" improvement from a treatment. Unfortunately, responder analyses have numerous methodological shortcomings, which preclude inferences concerning individual response to treatments and, thus, adoption into clinical practice. In this Viewpoint, we summarize 2 major limitations of responder analyses: (1) their thresholds of success involve arbitrary criteria and (2) responder analyses do not capture true individual treatment effects. J Orthop Sports Phys Ther 2023;53(XX):1-3. Epub: 20 June 2023. doi:10.2519/jospt.2023.11853.
Duke Scholars
Published In
J Orthop Sports Phys Ther
DOI
EISSN
1938-1344
Publication Date
November 2023
Volume
53
Issue
11
Start / End Page
652 / 654
Location
United States
Related Subject Headings
- Randomized Controlled Trials as Topic
- Orthopedics
- Humans
- 4207 Sports science and exercise
- 4201 Allied health and rehabilitation science
- 3202 Clinical sciences
- 1106 Human Movement and Sports Sciences
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Cook, C. E., Bejarano, G., Reneker, J., Vigotsky, A. D., & Riddle, D. L. (2023). Responder Analyses: A Methodological Mess. J Orthop Sports Phys Ther, 53(11), 652–654. https://doi.org/10.2519/jospt.2023.11853
Cook, Chad E., Geronimo Bejarano, Jennifer Reneker, Andrew D. Vigotsky, and Daniel L. Riddle. “Responder Analyses: A Methodological Mess.” J Orthop Sports Phys Ther 53, no. 11 (November 2023): 652–54. https://doi.org/10.2519/jospt.2023.11853.
Cook CE, Bejarano G, Reneker J, Vigotsky AD, Riddle DL. Responder Analyses: A Methodological Mess. J Orthop Sports Phys Ther. 2023 Nov;53(11):652–4.
Cook, Chad E., et al. “Responder Analyses: A Methodological Mess.” J Orthop Sports Phys Ther, vol. 53, no. 11, Nov. 2023, pp. 652–54. Pubmed, doi:10.2519/jospt.2023.11853.
Cook CE, Bejarano G, Reneker J, Vigotsky AD, Riddle DL. Responder Analyses: A Methodological Mess. J Orthop Sports Phys Ther. 2023 Nov;53(11):652–654.
Published In
J Orthop Sports Phys Ther
DOI
EISSN
1938-1344
Publication Date
November 2023
Volume
53
Issue
11
Start / End Page
652 / 654
Location
United States
Related Subject Headings
- Randomized Controlled Trials as Topic
- Orthopedics
- Humans
- 4207 Sports science and exercise
- 4201 Allied health and rehabilitation science
- 3202 Clinical sciences
- 1106 Human Movement and Sports Sciences
- 1103 Clinical Sciences