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Anatomical structures, cell types and biomarkers of the Human Reference Atlas.

Publication ,  Journal Article
Börner, K; Teichmann, SA; Quardokus, EM; Gee, JC; Browne, K; Osumi-Sutherland, D; Herr, BW; Bueckle, A; Paul, H; Haniffa, M; Jardine, L; He, Y ...
Published in: Nature cell biology
November 2021

The Human Reference Atlas (HRA) aims to map all of the cells of the human body to advance biomedical research and clinical practice. This Perspective presents collaborative work by members of 16 international consortia on two essential and interlinked parts of the HRA: (1) three-dimensional representations of anatomy that are linked to (2) tables that name and interlink major anatomical structures, cell types, plus biomarkers (ASCT+B). We discuss four examples that demonstrate the practical utility of the HRA.

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Published In

Nature cell biology

DOI

EISSN

1476-4679

ISSN

1465-7392

Publication Date

November 2021

Volume

23

Issue

11

Start / End Page

1117 / 1128

Related Subject Headings

  • Transcriptome
  • Single-Cell Analysis
  • Phenotype
  • Humans
  • High-Throughput Nucleotide Sequencing
  • Genomics
  • Disease
  • Developmental Biology
  • Computer Graphics
  • Cells
 

Citation

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ICMJE
MLA
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Börner, K., Teichmann, S. A., Quardokus, E. M., Gee, J. C., Browne, K., Osumi-Sutherland, D., … Weber, G. (2021). Anatomical structures, cell types and biomarkers of the Human Reference Atlas. Nature Cell Biology, 23(11), 1117–1128. https://doi.org/10.1038/s41556-021-00788-6
Börner, Katy, Sarah A. Teichmann, Ellen M. Quardokus, James C. Gee, Kristen Browne, David Osumi-Sutherland, Bruce W. Herr, et al. “Anatomical structures, cell types and biomarkers of the Human Reference Atlas.Nature Cell Biology 23, no. 11 (November 2021): 1117–28. https://doi.org/10.1038/s41556-021-00788-6.
Börner K, Teichmann SA, Quardokus EM, Gee JC, Browne K, Osumi-Sutherland D, et al. Anatomical structures, cell types and biomarkers of the Human Reference Atlas. Nature cell biology. 2021 Nov;23(11):1117–28.
Börner, Katy, et al. “Anatomical structures, cell types and biomarkers of the Human Reference Atlas.Nature Cell Biology, vol. 23, no. 11, Nov. 2021, pp. 1117–28. Epmc, doi:10.1038/s41556-021-00788-6.
Börner K, Teichmann SA, Quardokus EM, Gee JC, Browne K, Osumi-Sutherland D, Herr BW, Bueckle A, Paul H, Haniffa M, Jardine L, Bernard A, Ding S-L, Miller JA, Lin S, Halushka MK, Boppana A, Longacre TA, Hickey J, Lin Y, Valerius MT, He Y, Pryhuber G, Sun X, Jorgensen M, Radtke AJ, Wasserfall C, Ginty F, Ho J, Sunshine J, Beuschel RT, Brusko M, Lee S, Malhotra R, Jain S, Weber G. Anatomical structures, cell types and biomarkers of the Human Reference Atlas. Nature cell biology. 2021 Nov;23(11):1117–1128.

Published In

Nature cell biology

DOI

EISSN

1476-4679

ISSN

1465-7392

Publication Date

November 2021

Volume

23

Issue

11

Start / End Page

1117 / 1128

Related Subject Headings

  • Transcriptome
  • Single-Cell Analysis
  • Phenotype
  • Humans
  • High-Throughput Nucleotide Sequencing
  • Genomics
  • Disease
  • Developmental Biology
  • Computer Graphics
  • Cells