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A Nonlethal Case of Junctional Epidermolysis Bullosa and Congenital Pyloric Atresia: Compound Heterozygosity in a Patient with a Novel Integrin Beta 4 Gene Mutation.

Publication ,  Journal Article
Ko, L; Griggs, CL; Mylonas, KS; Masiakos, PT; Kroshinsky, D
Published in: J Pediatr
February 2018

We report a case of nonfatal junctional epidermolysis bullosa and pyloric atresia in a newborn. We identified a substitution (c.914C>T) for the integrin β4 gene that has been associated with favorable outcome. A novel mutation (c.2011T>G) of unknown significance was also found in this patient who is now thriving.

Duke Scholars

Published In

J Pediatr

DOI

EISSN

1097-6833

Publication Date

February 2018

Volume

193

Start / End Page

261 / 264.e1

Location

United States

Related Subject Headings

  • Skin
  • Pylorus
  • Plastic Surgery Procedures
  • Pediatrics
  • Mutation
  • Laparotomy
  • Integrin beta4
  • Infant, Newborn
  • Humans
  • Heterozygote
 

Citation

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ICMJE
MLA
NLM
Ko, L., Griggs, C. L., Mylonas, K. S., Masiakos, P. T., & Kroshinsky, D. (2018). A Nonlethal Case of Junctional Epidermolysis Bullosa and Congenital Pyloric Atresia: Compound Heterozygosity in a Patient with a Novel Integrin Beta 4 Gene Mutation. J Pediatr, 193, 261-264.e1. https://doi.org/10.1016/j.jpeds.2017.09.023
Ko, Lauren, Cornelia L. Griggs, Konstantinos S. Mylonas, Peter T. Masiakos, and Daniela Kroshinsky. “A Nonlethal Case of Junctional Epidermolysis Bullosa and Congenital Pyloric Atresia: Compound Heterozygosity in a Patient with a Novel Integrin Beta 4 Gene Mutation.J Pediatr 193 (February 2018): 261-264.e1. https://doi.org/10.1016/j.jpeds.2017.09.023.
Ko, Lauren, et al. “A Nonlethal Case of Junctional Epidermolysis Bullosa and Congenital Pyloric Atresia: Compound Heterozygosity in a Patient with a Novel Integrin Beta 4 Gene Mutation.J Pediatr, vol. 193, Feb. 2018, pp. 261-264.e1. Pubmed, doi:10.1016/j.jpeds.2017.09.023.
Journal cover image

Published In

J Pediatr

DOI

EISSN

1097-6833

Publication Date

February 2018

Volume

193

Start / End Page

261 / 264.e1

Location

United States

Related Subject Headings

  • Skin
  • Pylorus
  • Plastic Surgery Procedures
  • Pediatrics
  • Mutation
  • Laparotomy
  • Integrin beta4
  • Infant, Newborn
  • Humans
  • Heterozygote