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Measures of sleep are not routinely captured in trials assessing treatment outcomes in knee osteoarthritis - A scoping systematic review and call to action.

Publication ,  Journal Article
Feda, J; Miller, T; Young, JL; Neilson, B; Rhon, DI
Published in: Osteoarthr Cartil Open
December 2023

OBJECTIVE: To identify and map the extent to which trials for pain interventions in individuals with knee osteoarthritis (OA) track measures of sleep, characterize the type of sleep measure assessed, and assess their influence on pain-related effect sizes. DESIGN: A scoping review was conducted, searching seven bibliometric databases from 2000 to 2022. We included all randomized controlled trials with a primary purpose of assessing non-surgical pain management interventions for adults with knee OA. All non-surgical interventions and any comparator or control were included. Demographic data were pooled from all trials. RESULTS: 926 trials conducted in 61 countries met eligibility. Nineteen trials (2.1%) recorded some form of sleep assessment. Eleven trials (1.2%) assessed a formal index of sleep disturbance collected at multiple time points. No trials formally assessed the influence of sleep on the primary pain outcome (e.g., as a potential mediator), nor met the most recent guidelines for core data element recommendations regarding sleep assessment. CONCLUSION: This review highlights the paucity of sleep data captured and reported in randomized controlled trials for knee OA. The vast majority of trials addressing symptomatic knee OA do not capture sleep measures, significantly limiting the ability to accurately determine an intervention's effect on pain. Future research should include formal sleep-centric assessments measured at multiple time points to analyze sleep dysfunction and its relationship on treatment effects.

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Published In

Osteoarthr Cartil Open

DOI

EISSN

2665-9131

Publication Date

December 2023

Volume

5

Issue

4

Start / End Page

100400

Location

England

Related Subject Headings

  • 3202 Clinical sciences
 

Citation

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Feda, J., Miller, T., Young, J. L., Neilson, B., & Rhon, D. I. (2023). Measures of sleep are not routinely captured in trials assessing treatment outcomes in knee osteoarthritis - A scoping systematic review and call to action. Osteoarthr Cartil Open, 5(4), 100400. https://doi.org/10.1016/j.ocarto.2023.100400
Feda, Jessica, Tyler Miller, Jodi L. Young, Brett Neilson, and Daniel I. Rhon. “Measures of sleep are not routinely captured in trials assessing treatment outcomes in knee osteoarthritis - A scoping systematic review and call to action.Osteoarthr Cartil Open 5, no. 4 (December 2023): 100400. https://doi.org/10.1016/j.ocarto.2023.100400.
Feda, Jessica, et al. “Measures of sleep are not routinely captured in trials assessing treatment outcomes in knee osteoarthritis - A scoping systematic review and call to action.Osteoarthr Cartil Open, vol. 5, no. 4, Dec. 2023, p. 100400. Pubmed, doi:10.1016/j.ocarto.2023.100400.

Published In

Osteoarthr Cartil Open

DOI

EISSN

2665-9131

Publication Date

December 2023

Volume

5

Issue

4

Start / End Page

100400

Location

England

Related Subject Headings

  • 3202 Clinical sciences