Skip to main content

Ankylosing spondylitis and risk of venous thromboembolism: A systematic review and meta-analysis.

Publication ,  Journal Article
Ungprasert, P; Srivali, N; Kittanamongkolchai, W
Published in: Lung India
2016

BACKGROUND: Several immune-mediated inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus have been linked to an increased risk of venous thromboembolism (VTE). However, the data on ankylosing spondylitis (AS) are limited. METHODS: We conducted a systematic review and meta-analysis of observational studies that reported odds ratio, relative risk, hazard ratio, or standardized incidence ratio comparing the risk of VTE and possible pulmonary embolism (PE) in patients with AS versus non-AS participants. Pooled risk ratio and 95% confidence intervals were calculated using a random-effect, generic inverse variance method of DerSimonian and Laird. RESULTS: Of 423 potentially relevant articles, three studies met our inclusion criteria and thus, were included in the data analysis. The pooled risk ratio of VTE in patients with AS was 1.60 (95% confidence interval: 1.05-2.44). The statistical heterogeneity of this study was high with an I2 of 93%. CONCLUSION: Our study demonstrated a statistically significant increased VTE risk among patients with AS.

Duke Scholars

Published In

Lung India

DOI

ISSN

0970-2113

Publication Date

2016

Volume

33

Issue

6

Start / End Page

642 / 645

Location

India

Related Subject Headings

  • 3204 Immunology
  • 3201 Cardiovascular medicine and haematology
  • 1107 Immunology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ungprasert, P., Srivali, N., & Kittanamongkolchai, W. (2016). Ankylosing spondylitis and risk of venous thromboembolism: A systematic review and meta-analysis. Lung India, 33(6), 642–645. https://doi.org/10.4103/0970-2113.192862
Ungprasert, Patompong, Narat Srivali, and Wonngarm Kittanamongkolchai. “Ankylosing spondylitis and risk of venous thromboembolism: A systematic review and meta-analysis.Lung India 33, no. 6 (2016): 642–45. https://doi.org/10.4103/0970-2113.192862.
Ungprasert P, Srivali N, Kittanamongkolchai W. Ankylosing spondylitis and risk of venous thromboembolism: A systematic review and meta-analysis. Lung India. 2016;33(6):642–5.
Ungprasert, Patompong, et al. “Ankylosing spondylitis and risk of venous thromboembolism: A systematic review and meta-analysis.Lung India, vol. 33, no. 6, 2016, pp. 642–45. Pubmed, doi:10.4103/0970-2113.192862.
Ungprasert P, Srivali N, Kittanamongkolchai W. Ankylosing spondylitis and risk of venous thromboembolism: A systematic review and meta-analysis. Lung India. 2016;33(6):642–645.

Published In

Lung India

DOI

ISSN

0970-2113

Publication Date

2016

Volume

33

Issue

6

Start / End Page

642 / 645

Location

India

Related Subject Headings

  • 3204 Immunology
  • 3201 Cardiovascular medicine and haematology
  • 1107 Immunology
  • 1102 Cardiorespiratory Medicine and Haematology