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Agreement and disagreement between child-caregiver symptom and function reports in pediatric oncology.

Publication ,  Journal Article
Weaver, MS; Wang, J; Reeve, BB; Porter, AS; Baker, JN; Mack, JW; Thompson, AL; Wiener, L; Grossoehme, DH; Hinds, PS
Published in: Pediatr Blood Cancer
January 2024

BACKGROUND/OBJECTIVE: The use of patient-reported outcomes (PRO) is increasing in pediatric clinical practice and research, including in clinical trials. Treatment teams are now able to discern differences in symptom and function reports between children with cancer and their family caregivers. Few studies, however, have quantified such differences. DESIGN/METHODS: Children and caregivers were matched to create a dyad sample, and child/caregiver agreement of responses to the Patient-Reported Outcome Measurement Information System (PROMIS) Pediatric symptom and function measures were examined using the established minimally important difference (MID) value (three points) derived from these measures. Latent class analysis (LCA) was then used to analyze the status/patterns of response agreement. RESULTS: A total of 430 dyadic cases (dyads) were used for LCA modeling. Three classes of child-caregiver concordance resulted: (a) Agreement-caregiver and child within one MID (200 dyads); (b) Disagreement-caregiver underestimating symptoms (47 dyads with caregiver scores more than 1 MID lower than the child scores); and (c) Disagreement-caregiver overestimating symptoms (183 dyads with caregiver scores more than 1 MID higher than child scores). CONCLUSION: As PRO use increases in pediatric oncology, clinician identification of child/caregiver differences on symptom and function reports will help to distinguish family perceptions of cancer treatment impact. The treatment goal, in addition to mitigating symptom and function treatment-related burdens for the child and caregiver, may now also be to discern the direction and clinical meaning of the difference within the child-parent dyad.

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Published In

Pediatr Blood Cancer

DOI

EISSN

1545-5017

Publication Date

January 2024

Volume

71

Issue

1

Start / End Page

e30710

Location

United States

Related Subject Headings

  • Patient Reported Outcome Measures
  • Oncology & Carcinogenesis
  • Neoplasms
  • Medical Oncology
  • Humans
  • Child
  • Caregivers
  • 3213 Paediatrics
  • 3211 Oncology and carcinogenesis
  • 1114 Paediatrics and Reproductive Medicine
 

Citation

APA
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Weaver, M. S., Wang, J., Reeve, B. B., Porter, A. S., Baker, J. N., Mack, J. W., … Hinds, P. S. (2024). Agreement and disagreement between child-caregiver symptom and function reports in pediatric oncology. Pediatr Blood Cancer, 71(1), e30710. https://doi.org/10.1002/pbc.30710
Weaver, Meaghann S., Jichuan Wang, Bryce B. Reeve, Amy S. Porter, Justin N. Baker, Jennifer W. Mack, Amanda L. Thompson, Lori Wiener, Daniel H. Grossoehme, and Pamela S. Hinds. “Agreement and disagreement between child-caregiver symptom and function reports in pediatric oncology.Pediatr Blood Cancer 71, no. 1 (January 2024): e30710. https://doi.org/10.1002/pbc.30710.
Weaver MS, Wang J, Reeve BB, Porter AS, Baker JN, Mack JW, et al. Agreement and disagreement between child-caregiver symptom and function reports in pediatric oncology. Pediatr Blood Cancer. 2024 Jan;71(1):e30710.
Weaver, Meaghann S., et al. “Agreement and disagreement between child-caregiver symptom and function reports in pediatric oncology.Pediatr Blood Cancer, vol. 71, no. 1, Jan. 2024, p. e30710. Pubmed, doi:10.1002/pbc.30710.
Weaver MS, Wang J, Reeve BB, Porter AS, Baker JN, Mack JW, Thompson AL, Wiener L, Grossoehme DH, Hinds PS. Agreement and disagreement between child-caregiver symptom and function reports in pediatric oncology. Pediatr Blood Cancer. 2024 Jan;71(1):e30710.
Journal cover image

Published In

Pediatr Blood Cancer

DOI

EISSN

1545-5017

Publication Date

January 2024

Volume

71

Issue

1

Start / End Page

e30710

Location

United States

Related Subject Headings

  • Patient Reported Outcome Measures
  • Oncology & Carcinogenesis
  • Neoplasms
  • Medical Oncology
  • Humans
  • Child
  • Caregivers
  • 3213 Paediatrics
  • 3211 Oncology and carcinogenesis
  • 1114 Paediatrics and Reproductive Medicine