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Health-related quality of life and utility scores of patients with breast neoplasms in China: A multicenter cross-sectional survey.

Publication ,  Journal Article
Wang, L; Shi, J-F; Zhu, J; Huang, H-Y; Bai, Y-N; Liu, G-X; Liao, X-Z; Mao, A-Y; Ren, J-S; Sun, X-J; Guo, L-W; Fang, Y; Zhou, Q; Ma, H-M ...
Published in: Breast
June 2018

BACKGROUND: Health-related quality of life and utility scores of patients with breast cancer and precancerous lesions are sparse in China. This study aimed to derive utility scores of patients with breast cancer and precancer in China. MATERIAL AND METHODS: An interviewer-administered cross-sectional survey was conducted in 12 provinces across China from 2013 to 2014. The three-level EuroQol-5-Dimension instrument was used to evaluate quality of life, and utility scores were generated using the Chinese value set. Univariate and multivariate analyses were performed to explore the determinants of utility scores. RESULTS: In total, 2626 breast cancer and 471 precancer patients were included. Mean age was 49.1 for breast cancer and 41.4 years for precancer (p < 0.001). Among the five dimensions, pain/discomfort was the most reported problem, 53.9% in breast cancer and 29.3% in precancer patients. Mean (95% CI) utility scores for breast cancer and precancer patients were estimated as 0.887 (0.875-0.899) and 0.781 (0.774-0.788), and the scores of breast cancer at stage-I, stage-II, stage-III and stage-IV were 0.789 (0.774-0.805), 0.793 (0.783-0.802), 0.774 (0.759-0.788) and 0.686 (0.654-0.717), respectively. Mean (95% CI) visual analogue scale scores for breast cancer and precancer were 75.6 (74.0-77.3) and 72.8 (72.3-73.3). Multiple regression showed advanced clinical stage, lower educational level, lower household income, surgery treatment, and undergoing treatment were independently associated with lower utility scores for breast cancer patients. CONCLUSION: The utility scores deteriorate with the severity of breast neoplasms. Detailed utility scores of breast cancer and precancer are fundamental for further cost-utility analysis in China.

Duke Scholars

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Published In

Breast

DOI

EISSN

1532-3080

Publication Date

June 2018

Volume

39

Start / End Page

53 / 62

Location

Netherlands

Related Subject Headings

  • Surveys and Questionnaires
  • Socioeconomic Factors
  • Regression Analysis
  • Quality of Life
  • Precancerous Conditions
  • Patient Acceptance of Health Care
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Middle Aged
  • Income
 

Citation

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Wang, L., Shi, J.-F., Zhu, J., Huang, H.-Y., Bai, Y.-N., Liu, G.-X., … Health Economic Evaluation Working Group of the Cancer Screening Program in Urban China, . (2018). Health-related quality of life and utility scores of patients with breast neoplasms in China: A multicenter cross-sectional survey. Breast, 39, 53–62. https://doi.org/10.1016/j.breast.2018.03.004
Wang, Le, Ju-Fang Shi, Juan Zhu, Hui-Yao Huang, Ya-Na Bai, Guo-Xiang Liu, Xian-Zhen Liao, et al. “Health-related quality of life and utility scores of patients with breast neoplasms in China: A multicenter cross-sectional survey.Breast 39 (June 2018): 53–62. https://doi.org/10.1016/j.breast.2018.03.004.
Wang L, Shi J-F, Zhu J, Huang H-Y, Bai Y-N, Liu G-X, et al. Health-related quality of life and utility scores of patients with breast neoplasms in China: A multicenter cross-sectional survey. Breast. 2018 Jun;39:53–62.
Wang, Le, et al. “Health-related quality of life and utility scores of patients with breast neoplasms in China: A multicenter cross-sectional survey.Breast, vol. 39, June 2018, pp. 53–62. Pubmed, doi:10.1016/j.breast.2018.03.004.
Wang L, Shi J-F, Zhu J, Huang H-Y, Bai Y-N, Liu G-X, Liao X-Z, Mao A-Y, Ren J-S, Sun X-J, Guo L-W, Fang Y, Zhou Q, Ma H-M, Xing X-J, Zhu L, Song B-B, Du L-B, Mai L, Liu Y-Q, Ren Y, Lan L, Zhou J-Y, Qi X, Sun X-H, Lou P-A, Wu S-L, Li N, Zhang K, He J, Dai M, Health Economic Evaluation Working Group of the Cancer Screening Program in Urban China. Health-related quality of life and utility scores of patients with breast neoplasms in China: A multicenter cross-sectional survey. Breast. 2018 Jun;39:53–62.
Journal cover image

Published In

Breast

DOI

EISSN

1532-3080

Publication Date

June 2018

Volume

39

Start / End Page

53 / 62

Location

Netherlands

Related Subject Headings

  • Surveys and Questionnaires
  • Socioeconomic Factors
  • Regression Analysis
  • Quality of Life
  • Precancerous Conditions
  • Patient Acceptance of Health Care
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Middle Aged
  • Income