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Quantitative evaluation of vessel tracking techniques on coronary angiograms.

Publication ,  Journal Article
Sen, A; Lan, L; Doi, K; Hoffmann, KR
Published in: Med Phys
May 1999

Accurate, automated determination of vessel center lines is essential for two- and three-dimensional analysis of the coronary vascular tree. Therefore, we have been developing techniques for vessel tracking and for evaluating their accuracy and precision in clinical images. After points in vessels are manually indicated, the vessels are tracked automatically by means of a modified sector-search approach. The perimeters of sectors centered on previous tracking points are searched for the pixels with the maximum contrast. The sector size and radius are automatically adjusted based on local vessel tortuosity. The performance of the tracking technique in regions of high-intensity background is improved by application of a nonlinear adaptive filtering technique in which the vessel signal is effectively removed prior to background estimation. The tracking results were evaluated visually and by calculation of distances between the tracked and user-indicated centerlines, which were used as the "truth." Two hundred and fifty-six coronary vessels were tracked in 32 angiograms. Vessels as small as 0.6 mm in diameter were tracked accurately. This technique correctly tracked 255/256 (>99%) vessels based on an average of 2-3 indicated points per vessel. The one incorrect tracking result was due to a low signal-to-noise ratio (SNR<2). The distance between the tracked and the "true" centerlines ranged from 0.4 to 1.8 pixels, with an average of 0.8 pixels. These results indicate that this technique can provide a reliable basis for 2D and 3D vascular analysis.

Duke Scholars

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

May 1999

Volume

26

Issue

5

Start / End Page

698 / 706

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Models, Theoretical
  • Image Processing, Computer-Assisted
  • Coronary Angiography
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Sen, A., Lan, L., Doi, K., & Hoffmann, K. R. (1999). Quantitative evaluation of vessel tracking techniques on coronary angiograms. Med Phys, 26(5), 698–706. https://doi.org/10.1118/1.598575
Sen, A., L. Lan, K. Doi, and K. R. Hoffmann. “Quantitative evaluation of vessel tracking techniques on coronary angiograms.Med Phys 26, no. 5 (May 1999): 698–706. https://doi.org/10.1118/1.598575.
Sen A, Lan L, Doi K, Hoffmann KR. Quantitative evaluation of vessel tracking techniques on coronary angiograms. Med Phys. 1999 May;26(5):698–706.
Sen, A., et al. “Quantitative evaluation of vessel tracking techniques on coronary angiograms.Med Phys, vol. 26, no. 5, May 1999, pp. 698–706. Pubmed, doi:10.1118/1.598575.
Sen A, Lan L, Doi K, Hoffmann KR. Quantitative evaluation of vessel tracking techniques on coronary angiograms. Med Phys. 1999 May;26(5):698–706.

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

May 1999

Volume

26

Issue

5

Start / End Page

698 / 706

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Models, Theoretical
  • Image Processing, Computer-Assisted
  • Coronary Angiography
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences