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Evaluation of clinical breast MR imaging performed with prototype computer-aided diagnosis breast MR imaging workstation: reader study.

Publication ,  Journal Article
Shimauchi, A; Giger, ML; Bhooshan, N; Lan, L; Pesce, LL; Lee, JK; Abe, H; Newstead, GM
Published in: Radiology
March 2011

PURPOSE: To evaluate a computer-aided diagnosis (CADx) system for dynamic contrast material-enhanced magnetic resonance (MR) imaging and compare it with a currently used clinical method of interpreting breast MR image findings that includes the use of commercially available automated software for kinetic image data processing and visualization. MATERIALS AND METHODS: In this HIPAA-compliant, institutional review board-approved study, a training set of 121 breast lesions (77 malignant, 44 benign) was used to train the CADx system. After practicing with 10 training cases, six breast imaging radiologists assessed the likelihood of malignancy and the need for biopsy with a separate test set of 60 lesions (30 malignant, 30 benign). Their performances in differentiating between benign and malignant breast lesions both without (conventional lesion viewing, output from commercially available breast MR imaging analysis software) and with the aid of the CADx workstation (with classification yielding an estimation of the probability of malignancy for each lesion) were evaluated with receiver operating characteristic analysis. RESULTS: When CADx was used, the average performance of the radiologists was significantly improved, as indicated by increases in mean area under the receiver operating characteristic curve (from 0.80 to 0.84, P = .007), mean sensitivity (from 83% to 88%, P = .001), and average number of biopsy recommendations for malignant cases (1.7 more biopsies for malignant lesions with use of CADx, P = .032). Although the mean specificity improved (from 50% to 53%), the improvement was not significant (P = .2). CONCLUSION: Use of the CADx system improved the radiologists' performance in differentiating between malignant and benign MR imaging-depicted breast lesions.

Duke Scholars

Published In

Radiology

DOI

EISSN

1527-1315

Publication Date

March 2011

Volume

258

Issue

3

Start / End Page

696 / 704

Location

United States

Related Subject Headings

  • Retrospective Studies
  • ROC Curve
  • Observer Variation
  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Imaging
  • Image Enhancement
  • Humans
  • Gadolinium DTPA
  • Female
  • Diagnosis, Differential
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Shimauchi, A., Giger, M. L., Bhooshan, N., Lan, L., Pesce, L. L., Lee, J. K., … Newstead, G. M. (2011). Evaluation of clinical breast MR imaging performed with prototype computer-aided diagnosis breast MR imaging workstation: reader study. Radiology, 258(3), 696–704. https://doi.org/10.1148/radiol.10100409
Shimauchi, Akiko, Maryellen L. Giger, Neha Bhooshan, Li Lan, Lorenzo L. Pesce, John K. Lee, Hiroyuki Abe, and Gillian M. Newstead. “Evaluation of clinical breast MR imaging performed with prototype computer-aided diagnosis breast MR imaging workstation: reader study.Radiology 258, no. 3 (March 2011): 696–704. https://doi.org/10.1148/radiol.10100409.
Shimauchi A, Giger ML, Bhooshan N, Lan L, Pesce LL, Lee JK, et al. Evaluation of clinical breast MR imaging performed with prototype computer-aided diagnosis breast MR imaging workstation: reader study. Radiology. 2011 Mar;258(3):696–704.
Shimauchi, Akiko, et al. “Evaluation of clinical breast MR imaging performed with prototype computer-aided diagnosis breast MR imaging workstation: reader study.Radiology, vol. 258, no. 3, Mar. 2011, pp. 696–704. Pubmed, doi:10.1148/radiol.10100409.
Shimauchi A, Giger ML, Bhooshan N, Lan L, Pesce LL, Lee JK, Abe H, Newstead GM. Evaluation of clinical breast MR imaging performed with prototype computer-aided diagnosis breast MR imaging workstation: reader study. Radiology. 2011 Mar;258(3):696–704.

Published In

Radiology

DOI

EISSN

1527-1315

Publication Date

March 2011

Volume

258

Issue

3

Start / End Page

696 / 704

Location

United States

Related Subject Headings

  • Retrospective Studies
  • ROC Curve
  • Observer Variation
  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Imaging
  • Image Enhancement
  • Humans
  • Gadolinium DTPA
  • Female
  • Diagnosis, Differential