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Patient Selection and End Point Definitions for Decongestion Studies in Acute Decompensated Heart Failure: Part 2.

Publication ,  Journal Article
Georges, G; Fudim, M; Burkhoff, D; Leon, MB; Généreux, P
Published in: J Soc Cardiovasc Angiogr Interv
2023

Congestion is the most common manifestation of acute decompensated heart failure (ADHF). Residual congestion despite initial medical therapy is common and is recognized to be associated with worse outcomes; however, there are currently no standardized definition regarding decongestion end point. In the second part of this 2-part review, we provide a critical appraisal of decongestion definitions previously used in ADHF studies, review alternative metrics to define severity of volume overload, and propose a more granular 4-class congestion grading scheme and decongestion end point definitions that could potentially be included in future ADHF trials and consensus definitions.

Duke Scholars

Published In

J Soc Cardiovasc Angiogr Interv

DOI

EISSN

2772-9303

Publication Date

2023

Volume

2

Issue

6Part B

Start / End Page

101059

Location

United States
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Georges, G., Fudim, M., Burkhoff, D., Leon, M. B., & Généreux, P. (2023). Patient Selection and End Point Definitions for Decongestion Studies in Acute Decompensated Heart Failure: Part 2. J Soc Cardiovasc Angiogr Interv, 2(6Part B), 101059. https://doi.org/10.1016/j.jscai.2023.101059
Georges, Gabriel, Marat Fudim, Daniel Burkhoff, Martin B. Leon, and Philippe Généreux. “Patient Selection and End Point Definitions for Decongestion Studies in Acute Decompensated Heart Failure: Part 2.J Soc Cardiovasc Angiogr Interv 2, no. 6Part B (2023): 101059. https://doi.org/10.1016/j.jscai.2023.101059.
Georges G, Fudim M, Burkhoff D, Leon MB, Généreux P. Patient Selection and End Point Definitions for Decongestion Studies in Acute Decompensated Heart Failure: Part 2. J Soc Cardiovasc Angiogr Interv. 2023;2(6Part B):101059.
Georges, Gabriel, et al. “Patient Selection and End Point Definitions for Decongestion Studies in Acute Decompensated Heart Failure: Part 2.J Soc Cardiovasc Angiogr Interv, vol. 2, no. 6Part B, 2023, p. 101059. Pubmed, doi:10.1016/j.jscai.2023.101059.
Georges G, Fudim M, Burkhoff D, Leon MB, Généreux P. Patient Selection and End Point Definitions for Decongestion Studies in Acute Decompensated Heart Failure: Part 2. J Soc Cardiovasc Angiogr Interv. 2023;2(6Part B):101059.

Published In

J Soc Cardiovasc Angiogr Interv

DOI

EISSN

2772-9303

Publication Date

2023

Volume

2

Issue

6Part B

Start / End Page

101059

Location

United States