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A predictive survival model for patients with head and neck squamous cell carcinoma treated with immune check point inhibitors.

Publication ,  Journal Article
Bonomi, M; Bhateja, P; Issa, M; Klamer, B; Pan, X; Blakaj, A; Karivedu, V; Mousa, L; Mitchell, D; Gamez, M; Kang, S; Seim, NB; Old, M ...
Published in: Oral Oncol
November 2020

BACKGROUND: ICIs have expanded treatment options for HNSCC. A minority of the patients respond to these expensive treatments. PATIENTS AND METHODS: This is a single institutional retrospective review on 121 unresectable or metastatic HNSCC patients treated with ICIs. We predicted that inflammatory markers available through routine blood work, in addition to clinical characteristics may divide patients into groups more or less likely to respond to these agents. Here we develop and internally validate our nomogram to predict survival in patients treated with ICIs.

Duke Scholars

Published In

Oral Oncol

DOI

EISSN

1879-0593

Publication Date

November 2020

Volume

110

Start / End Page

104900

Location

England

Related Subject Headings

  • Treatment Outcome
  • Survival Rate
  • Squamous Cell Carcinoma of Head and Neck
  • Retrospective Studies
  • Proportional Hazards Models
  • Prognosis
  • Oncology & Carcinogenesis
  • Molecular Targeted Therapy
  • Middle Aged
  • Male
 

Citation

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MLA
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Bonomi, M., Bhateja, P., Issa, M., Klamer, B., Pan, X., Blakaj, A., … Blakaj, D. (2020). A predictive survival model for patients with head and neck squamous cell carcinoma treated with immune check point inhibitors. Oral Oncol, 110, 104900. https://doi.org/10.1016/j.oraloncology.2020.104900
Bonomi, M., P. Bhateja, M. Issa, B. Klamer, X. Pan, A. Blakaj, V. Karivedu, et al. “A predictive survival model for patients with head and neck squamous cell carcinoma treated with immune check point inhibitors.Oral Oncol 110 (November 2020): 104900. https://doi.org/10.1016/j.oraloncology.2020.104900.
Bonomi M, Bhateja P, Issa M, Klamer B, Pan X, Blakaj A, et al. A predictive survival model for patients with head and neck squamous cell carcinoma treated with immune check point inhibitors. Oral Oncol. 2020 Nov;110:104900.
Bonomi, M., et al. “A predictive survival model for patients with head and neck squamous cell carcinoma treated with immune check point inhibitors.Oral Oncol, vol. 110, Nov. 2020, p. 104900. Pubmed, doi:10.1016/j.oraloncology.2020.104900.
Bonomi M, Bhateja P, Issa M, Klamer B, Pan X, Blakaj A, Karivedu V, Mousa L, Mitchell D, Gamez M, Kang S, Seim NB, Old M, Carrau R, Rocco J, Blakaj D. A predictive survival model for patients with head and neck squamous cell carcinoma treated with immune check point inhibitors. Oral Oncol. 2020 Nov;110:104900.
Journal cover image

Published In

Oral Oncol

DOI

EISSN

1879-0593

Publication Date

November 2020

Volume

110

Start / End Page

104900

Location

England

Related Subject Headings

  • Treatment Outcome
  • Survival Rate
  • Squamous Cell Carcinoma of Head and Neck
  • Retrospective Studies
  • Proportional Hazards Models
  • Prognosis
  • Oncology & Carcinogenesis
  • Molecular Targeted Therapy
  • Middle Aged
  • Male