The KRAS tour: Studying metabolic reprogramming in isogenic pancreatic cancer organoids.
Publication
, Journal Article
Bose, S; Shen, X
Published in: Cell Stem Cell
January 4, 2024
Using an isogenic organoid platform to model pancreatic cancer, Duan et al. establish an important link between mutant KRAS and cholesterol metabolism and identify perhexiline maleate as a possible therapeutic to target this relationship.
Duke Scholars
Published In
Cell Stem Cell
DOI
EISSN
1875-9777
Publication Date
January 4, 2024
Volume
31
Issue
1
Start / End Page
1 / 2
Location
United States
Related Subject Headings
- Proto-Oncogene Proteins p21(ras)
- Pancreatic Neoplasms
- Organoids
- Metabolic Reprogramming
- Lipid Metabolism
- Humans
- Developmental Biology
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 11 Medical and Health Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Bose, S., & Shen, X. (2024). The KRAS tour: Studying metabolic reprogramming in isogenic pancreatic cancer organoids. Cell Stem Cell, 31(1), 1–2. https://doi.org/10.1016/j.stem.2023.12.010
Bose, Shree, and Xiling Shen. “The KRAS tour: Studying metabolic reprogramming in isogenic pancreatic cancer organoids.” Cell Stem Cell 31, no. 1 (January 4, 2024): 1–2. https://doi.org/10.1016/j.stem.2023.12.010.
Bose S, Shen X. The KRAS tour: Studying metabolic reprogramming in isogenic pancreatic cancer organoids. Cell Stem Cell. 2024 Jan 4;31(1):1–2.
Bose, Shree, and Xiling Shen. “The KRAS tour: Studying metabolic reprogramming in isogenic pancreatic cancer organoids.” Cell Stem Cell, vol. 31, no. 1, Jan. 2024, pp. 1–2. Pubmed, doi:10.1016/j.stem.2023.12.010.
Bose S, Shen X. The KRAS tour: Studying metabolic reprogramming in isogenic pancreatic cancer organoids. Cell Stem Cell. 2024 Jan 4;31(1):1–2.
Published In
Cell Stem Cell
DOI
EISSN
1875-9777
Publication Date
January 4, 2024
Volume
31
Issue
1
Start / End Page
1 / 2
Location
United States
Related Subject Headings
- Proto-Oncogene Proteins p21(ras)
- Pancreatic Neoplasms
- Organoids
- Metabolic Reprogramming
- Lipid Metabolism
- Humans
- Developmental Biology
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 11 Medical and Health Sciences