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Supplemental Patch Testing Identifies Allergens Missed by Standard Screening Series.

Publication ,  Journal Article
Atwater, AR; Liu, B; Walsh, R; Bembry, R; Ward, JM; Green, CL
Published in: Dermatitis
2024

Background: Supplemental patch testing is an adjunct to standard patch test screening series. Objective: To determine the demographics, characteristics, frequency, relevance, and interpretation of patch test reactions for supplemental patch testing. Methods: Retrospective study of patients tested 2017-2020 with North American Contact Dermatitis Group (NACDG) and supplemental screening series (Supplemental Series A [SSA], Supplemental Series B [SSB]). Demographics, characteristics, reaction strengths, relevance, and final interpretation were recorded. Results: Cohort included 791 patients; 73.5% female, 68.6% age >40 years. 74.1% were White, 15.2% Black, 5.7% Asian, and 1.5% Hispanic. The most common Dermatitis sites were scattered/generalized (27.2%), face (24.0%), and hands (23.5%). For 2017-2018 and 2019-2020, respectively, 82% (318/388) and 78.4% (316/403) had ≥1 "allergic" reaction. In addition, 13.5% (52/385) and 11.7% (47/403) had SSA reactions, and 38.1% (115/302) and 31.5% (101/321) had SSB reactions. In the 87 (2017-2018) and 99 (2019-2020) patients with negative NACDG testing, 17 (19.5%) and 12 (12.1%) had supplemental reactions. Of the 34 supplemental allergens with reaction frequency ≥1%, 58.8% (20/34) are not part of the American Contact Dermatitis Society 90 (2020) or NACDG 2021-2022 screening series. The highest frequency allergens from this group were dodecyl and octyl gallate, cinnamic alcohol, phenyl salicylate, hexahydro-1,3,5-tris-(2-hydroxyethyl) triazine, and abitol. Conclusions: Supplemental patch testing identifies additional relevant allergens in patients with suspected allergic contact Dermatitis.

Duke Scholars

Published In

Dermatitis

DOI

EISSN

2162-5220

Publication Date

2024

Volume

35

Issue

4

Start / End Page

366 / 372

Location

United States

Related Subject Headings

  • Young Adult
  • Retrospective Studies
  • Patch Tests
  • Middle Aged
  • Male
  • Humans
  • Female
  • Dermatology & Venereal Diseases
  • Dermatitis, Allergic Contact
  • Allergens
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Atwater, A. R., Liu, B., Walsh, R., Bembry, R., Ward, J. M., & Green, C. L. (2024). Supplemental Patch Testing Identifies Allergens Missed by Standard Screening Series. Dermatitis, 35(4), 366–372. https://doi.org/10.1089/derm.2023.0310
Atwater, Amber Reck, Beiyu Liu, Rabina Walsh, Raina Bembry, Jordan Maxwell Ward, and Cynthia L. Green. “Supplemental Patch Testing Identifies Allergens Missed by Standard Screening Series.Dermatitis 35, no. 4 (2024): 366–72. https://doi.org/10.1089/derm.2023.0310.
Atwater AR, Liu B, Walsh R, Bembry R, Ward JM, Green CL. Supplemental Patch Testing Identifies Allergens Missed by Standard Screening Series. Dermatitis. 2024;35(4):366–72.
Atwater, Amber Reck, et al. “Supplemental Patch Testing Identifies Allergens Missed by Standard Screening Series.Dermatitis, vol. 35, no. 4, 2024, pp. 366–72. Pubmed, doi:10.1089/derm.2023.0310.
Atwater AR, Liu B, Walsh R, Bembry R, Ward JM, Green CL. Supplemental Patch Testing Identifies Allergens Missed by Standard Screening Series. Dermatitis. 2024;35(4):366–372.

Published In

Dermatitis

DOI

EISSN

2162-5220

Publication Date

2024

Volume

35

Issue

4

Start / End Page

366 / 372

Location

United States

Related Subject Headings

  • Young Adult
  • Retrospective Studies
  • Patch Tests
  • Middle Aged
  • Male
  • Humans
  • Female
  • Dermatology & Venereal Diseases
  • Dermatitis, Allergic Contact
  • Allergens