Salactin, a dynamically unstable actin homolog in Haloarchaea.
Publication
, Journal Article
Zheng, J; Mallon, J; Lammers, A; Rados, T; Litschel, T; Moody, ERR; Ramirez-Diaz, DA; Schmid, A; Williams, TA; Bisson-Filho, AW; Garner, E
Published in: mBio
December 2023
Protein filaments play important roles in many biological processes. We discovered an actin homolog in halophilic archaea, which we call Salactin. Just like the filaments that segregate DNA in eukaryotes, Salactin grows out of the cell poles towards the middle, and then quickly depolymerizes, a behavior known as dynamic instability. Furthermore, we see that Salactin affects the distribution of DNA in daughter cells when cells are grown in low-phosphate media, suggesting Salactin filaments might be involved in segregating DNA when the cell has only a few copies of the chromosome.
Duke Scholars
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Published In
mBio
DOI
EISSN
2150-7511
ISSN
2150-7511
Publication Date
December 2023
Volume
14
Issue
6
Start / End Page
e0227223
Related Subject Headings
- Archaeal Proteins
- Actins
- 3207 Medical microbiology
- 3107 Microbiology
- 3101 Biochemistry and cell biology
- 0605 Microbiology
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Chicago
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MLA
NLM
Zheng, J., Mallon, J., Lammers, A., Rados, T., Litschel, T., Moody, E. R. R., … Garner, E. (2023). Salactin, a dynamically unstable actin homolog in Haloarchaea. MBio, 14(6), e0227223. https://doi.org/10.1128/mbio.02272-23
Zheng, Jenny, John Mallon, Alex Lammers, Theopi Rados, Thomas Litschel, Edmund R. R. Moody, Diego A. Ramirez-Diaz, et al. “Salactin, a dynamically unstable actin homolog in Haloarchaea.” MBio 14, no. 6 (December 2023): e0227223. https://doi.org/10.1128/mbio.02272-23.
Zheng J, Mallon J, Lammers A, Rados T, Litschel T, Moody ERR, et al. Salactin, a dynamically unstable actin homolog in Haloarchaea. mBio. 2023 Dec;14(6):e0227223.
Zheng, Jenny, et al. “Salactin, a dynamically unstable actin homolog in Haloarchaea.” MBio, vol. 14, no. 6, Dec. 2023, p. e0227223. Epmc, doi:10.1128/mbio.02272-23.
Zheng J, Mallon J, Lammers A, Rados T, Litschel T, Moody ERR, Ramirez-Diaz DA, Schmid A, Williams TA, Bisson-Filho AW, Garner E. Salactin, a dynamically unstable actin homolog in Haloarchaea. mBio. 2023 Dec;14(6):e0227223.
Published In
mBio
DOI
EISSN
2150-7511
ISSN
2150-7511
Publication Date
December 2023
Volume
14
Issue
6
Start / End Page
e0227223
Related Subject Headings
- Archaeal Proteins
- Actins
- 3207 Medical microbiology
- 3107 Microbiology
- 3101 Biochemistry and cell biology
- 0605 Microbiology