Skip to main content

Salactin, a dynamically unstable actin homolog in Haloarchaea.

Publication ,  Journal Article
Zheng, J; Mallon, J; Lammers, A; Rados, T; Litschel, T; Moody, ERR; Ramirez-Diaz, DA; Schmid, A; Williams, TA; Bisson-Filho, AW; Garner, E
Published in: mBio
November 2023

Protein filaments play important roles in many biological processes. We discovered an actin homolog in halophilic archaea, which we call Salactin. Just like the filaments that segregate DNA in eukaryotes, Salactin grows out of the cell poles towards the middle, and then quickly depolymerizes, a behavior known as dynamic instability. Furthermore, we see that Salactin affects the distribution of DNA in daughter cells when cells are grown in low-phosphate media, suggesting Salactin filaments might be involved in segregating DNA when the cell has only a few copies of the chromosome.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

mBio

DOI

EISSN

2150-7511

ISSN

2150-7511

Publication Date

November 2023

Start / End Page

e0227223

Related Subject Headings

  • 3207 Medical microbiology
  • 3107 Microbiology
  • 3101 Biochemistry and cell biology
  • 0605 Microbiology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Zheng, J., Mallon, J., Lammers, A., Rados, T., Litschel, T., Moody, E. R. R., … Garner, E. (2023). Salactin, a dynamically unstable actin homolog in Haloarchaea. MBio, e0227223. https://doi.org/10.1128/mbio.02272-23
Zheng, Jenny, John Mallon, Alex Lammers, Theopi Rados, Thomas Litschel, Edmund R. R. Moody, Diego A. Ramirez-Diaz, et al. “Salactin, a dynamically unstable actin homolog in Haloarchaea.MBio, November 2023, e0227223. https://doi.org/10.1128/mbio.02272-23.
Zheng J, Mallon J, Lammers A, Rados T, Litschel T, Moody ERR, et al. Salactin, a dynamically unstable actin homolog in Haloarchaea. mBio. 2023 Nov;e0227223.
Zheng, Jenny, et al. “Salactin, a dynamically unstable actin homolog in Haloarchaea.MBio, Nov. 2023, p. e0227223. Epmc, doi:10.1128/mbio.02272-23.
Zheng J, Mallon J, Lammers A, Rados T, Litschel T, Moody ERR, Ramirez-Diaz DA, Schmid A, Williams TA, Bisson-Filho AW, Garner E. Salactin, a dynamically unstable actin homolog in Haloarchaea. mBio. 2023 Nov;e0227223.

Published In

mBio

DOI

EISSN

2150-7511

ISSN

2150-7511

Publication Date

November 2023

Start / End Page

e0227223

Related Subject Headings

  • 3207 Medical microbiology
  • 3107 Microbiology
  • 3101 Biochemistry and cell biology
  • 0605 Microbiology