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Computed Tomography Volumetry of Bone Cement: Retrospective Blinded Validation of Commercially Available Semi-automated Edge Detection Software.

Publication ,  Journal Article
Sag, AA; Barral, E; Thompson, RE; Goodwin, CR; Ronald, J
Published in: J Comput Assist Tomogr
July 2024

OBJECTIVE: Cement volumes are increasingly linked to orthopedic oncology and neurosurgical outcomes (construct durability, adjacent fracture), but manual cement volumetry remains time prohibitive. The authors aim to report performance of PACS-integrated volumetric software specifically for barium-enhanced polymethylmethacrylate cement. METHODS: Institutional review board-approved single-institution retrospective review of patients from 2019-2022 undergoing kyphoplasty for pathological compression fractures with a quantitative cement infuser providing true cement volume. An operator blinded to true cement volumes retrospectively performed software-assisted volumetry on follow-up computed tomography scans. RESULTS: Included were 91 kyphoplasty levels in 56 patients: mean age, 62 years (range, 34-85 years), 73% female. True cement volume (available for 44 of 66 procedures) was mean 4.5 mL per level (range, 1.2-15.6 mL). Measured cement volume (available for all procedures) yielded a mean of 6.1 mL per level (range, 1.5-27.9 mL). For the 57 levels (39 patients) where both true and measured cement volumes were available, linear regression intercept and slope were 1.46 (95% CI = 0.97-1.95, P < 0.001) and 0.52 (CI = 0.47-0.57, P < 0.001), respectively, suggesting measured volume averaged 1.46 mL greater than true volume, with each additional milliliter of measured volume corresponding to approximately 0.52 mL of true volume. There was no significant difference in the relationship between estimated and actual cement volume in thoracic levels (intercept = -0.24, CI = -1.13 to 0.66, P = 0.61; slope = 0.03, CI = -0.14 to 0.19, P = 0.73) compared with lumbar levels. The goodness-of-fit of the regression model was strong ( R2 = 0.81). Discrepancies ranged from 90% underestimation to 52% overestimation; average, 17% overestimation. CONCLUSIONS: Semi-automated volumetry maintained a strong correlation with true volumes across the thoracic and lumbar curvatures, overestimating cement volume by a mean of 17% or 1.46 mL.

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Published In

J Comput Assist Tomogr

DOI

EISSN

1532-3145

Publication Date

July 2024

Volume

48

Issue

4

Start / End Page

669 / 672

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Spinal Fractures
  • Software
  • Retrospective Studies
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Kyphoplasty
  • Humans
  • Fractures, Compression
 

Citation

APA
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MLA
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Sag, A. A., Barral, E., Thompson, R. E., Goodwin, C. R., & Ronald, J. (2024). Computed Tomography Volumetry of Bone Cement: Retrospective Blinded Validation of Commercially Available Semi-automated Edge Detection Software. J Comput Assist Tomogr, 48(4), 669–672. https://doi.org/10.1097/RCT.0000000000001588
Sag, Alan A., Ernest Barral, Russell E. Thompson, C Rory Goodwin, and James Ronald. “Computed Tomography Volumetry of Bone Cement: Retrospective Blinded Validation of Commercially Available Semi-automated Edge Detection Software.J Comput Assist Tomogr 48, no. 4 (July 2024): 669–72. https://doi.org/10.1097/RCT.0000000000001588.
Sag AA, Barral E, Thompson RE, Goodwin CR, Ronald J. Computed Tomography Volumetry of Bone Cement: Retrospective Blinded Validation of Commercially Available Semi-automated Edge Detection Software. J Comput Assist Tomogr. 2024 Jul;48(4):669–72.
Sag, Alan A., et al. “Computed Tomography Volumetry of Bone Cement: Retrospective Blinded Validation of Commercially Available Semi-automated Edge Detection Software.J Comput Assist Tomogr, vol. 48, no. 4, July 2024, pp. 669–72. Pubmed, doi:10.1097/RCT.0000000000001588.
Sag AA, Barral E, Thompson RE, Goodwin CR, Ronald J. Computed Tomography Volumetry of Bone Cement: Retrospective Blinded Validation of Commercially Available Semi-automated Edge Detection Software. J Comput Assist Tomogr. 2024 Jul;48(4):669–672.

Published In

J Comput Assist Tomogr

DOI

EISSN

1532-3145

Publication Date

July 2024

Volume

48

Issue

4

Start / End Page

669 / 672

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Spinal Fractures
  • Software
  • Retrospective Studies
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Kyphoplasty
  • Humans
  • Fractures, Compression