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Development of an ultra-short measure of eight domains of health-related quality of life for research and clinical care: the patient-reported outcomes measurement information system® PROMIS®-16 profile.

Publication ,  Journal Article
Edelen, MO; Zeng, C; Hays, RD; Rodriguez, A; Hanmer, J; Baumhauer, J; Cella, D; Reeve, BB; Herman, PM
Published in: Qual Life Res
February 6, 2024

PURPOSE: We describe development of a short health-related quality of life measure, the patient-reported outcomes measurement information system® (PROMIS®)-16 Profile, which generates domain-specific scores for physical function, ability to participate in social roles and activities, anxiety, depression, sleep disturbance, pain interference, cognitive function, and fatigue. METHODS: An empirical evaluation of 50 candidate PROMIS items and item pairs was conducted using data from a sample of 5775 respondents from Amazon's Mechanical Turk (MTurk). Results and item response theory information curves for a subset of item pairs were presented and discussed in a stakeholder meeting to narrow the candidate item sets. A survey of the stakeholders and 124 MTurk adults was conducted to solicit preferences among remaining candidate items and finalize the measure. RESULTS: Empirical evaluation showed minimal differences in basic descriptive statistics (e.g., means, correlations) and associations with the PROMIS-29 + 2 Profile, thus item pairs were further considered primarily based on item properties and content. Stakeholders discussed and identified subsets of candidate item pairs for six domains, and final item pairs were agreed upon for two domains. Final items were selected based on stakeholder and MTurk-respondent preferences. The PROMIS-16 profile generates eight domain scores with strong psychometric properties. CONCLUSION: The PROMIS-16 Profile provides an attractive brief measure of eight distinct domains of health-related quality of life, representing an ideal screening tool for clinical care, which can help clinicians quickly identify distinct areas of concern that may require further assessment and follow-up. Further research is needed to confirm and extend these findings.

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Published In

Qual Life Res

DOI

EISSN

1573-2649

Publication Date

February 6, 2024

Location

Netherlands

Related Subject Headings

  • Health Policy & Services
  • 44 Human society
  • 42 Health sciences
  • 1701 Psychology
  • 1117 Public Health and Health Services
 

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Edelen, M. O., Zeng, C., Hays, R. D., Rodriguez, A., Hanmer, J., Baumhauer, J., … Herman, P. M. (2024). Development of an ultra-short measure of eight domains of health-related quality of life for research and clinical care: the patient-reported outcomes measurement information system® PROMIS®-16 profile. Qual Life Res. https://doi.org/10.1007/s11136-023-03597-6
Edelen, Maria Orlando, Chengbo Zeng, Ron D. Hays, Anthony Rodriguez, Janel Hanmer, Judy Baumhauer, David Cella, Bryce B. Reeve, and Patricia M. Herman. “Development of an ultra-short measure of eight domains of health-related quality of life for research and clinical care: the patient-reported outcomes measurement information system® PROMIS®-16 profile.Qual Life Res, February 6, 2024. https://doi.org/10.1007/s11136-023-03597-6.
Journal cover image

Published In

Qual Life Res

DOI

EISSN

1573-2649

Publication Date

February 6, 2024

Location

Netherlands

Related Subject Headings

  • Health Policy & Services
  • 44 Human society
  • 42 Health sciences
  • 1701 Psychology
  • 1117 Public Health and Health Services