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Use of Calcium Modification During Percutaneous Coronary Intervention After Introduction of Coronary Intravascular Lithotripsy

Publication ,  Journal Article
Butala, NM; Waldo, SW; Secemsky, EA; Kennedy, KF; Spertus, JA; Rymer, JA; Rao, SV; Messenger, JC; Yeh, RW
Published in: Journal of the Society for Cardiovascular Angiography and Interventions
February 1, 2024

Background: Calcified coronary lesions are a challenge for percutaneous coronary interventions (PCIs). Coronary intravascular lithotripsy (IVL) is a novel calcium modification technology approved for commercial use in February 2021, but little is known about its uptake in US clinical practice. Methods: We described trends in use of calcium modification strategies, variation in use across hospitals, and predictors of calcium modification and IVL use in PCI. We included National Cardiovascular Data Registry CathPCI Registry patients who underwent PCI between April 1, 2018, and December 31, 2022. We examined trends and hospital variation in calcium modification and IVL use. We used multivariate hierarchical logistic regression to identify predictors of calcium modification and IVL use at hospitals in 2022. Results: Of 2,733,494 PCIs across 1676 hospitals over 4.75 years, 11.4% were performed with calcium modification. Coronary IVL use increased rapidly from 0% of PCIs in Q4 2020 to 7.8% of PCIs in Q4 2022, which was accompanied by an overall increase in use of all calcium modification strategies (11.1%-16.0%) during this period with a slight corresponding decrease in coronary atherectomy use (5.4%-4.4%). In 2022, there was wide variation in IVL use across hospitals (median, 3.86%; IQR, 0%-8.19%), with IVL being the most common calcium modification strategy in 48% of hospitals. The treating hospital was the strongest predictor of calcium modification (median odds ratio [OR], 2.49; 95% CI, 2.40-2.57) and IVL use (median OR, 2.89; 95% CI, 2.74-3.04). Conclusions: IVL has rapidly changed the landscape of calcium modification use for PCI, although there remains wide variation across hospitals.

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Published In

Journal of the Society for Cardiovascular Angiography and Interventions

DOI

EISSN

2772-9303

Publication Date

February 1, 2024

Volume

3

Issue

2
 

Citation

APA
Chicago
ICMJE
MLA
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Butala, N. M., Waldo, S. W., Secemsky, E. A., Kennedy, K. F., Spertus, J. A., Rymer, J. A., … Yeh, R. W. (2024). Use of Calcium Modification During Percutaneous Coronary Intervention After Introduction of Coronary Intravascular Lithotripsy. Journal of the Society for Cardiovascular Angiography and Interventions, 3(2). https://doi.org/10.1016/j.jscai.2023.101254
Butala, N. M., S. W. Waldo, E. A. Secemsky, K. F. Kennedy, J. A. Spertus, J. A. Rymer, S. V. Rao, J. C. Messenger, and R. W. Yeh. “Use of Calcium Modification During Percutaneous Coronary Intervention After Introduction of Coronary Intravascular Lithotripsy.” Journal of the Society for Cardiovascular Angiography and Interventions 3, no. 2 (February 1, 2024). https://doi.org/10.1016/j.jscai.2023.101254.
Butala NM, Waldo SW, Secemsky EA, Kennedy KF, Spertus JA, Rymer JA, et al. Use of Calcium Modification During Percutaneous Coronary Intervention After Introduction of Coronary Intravascular Lithotripsy. Journal of the Society for Cardiovascular Angiography and Interventions. 2024 Feb 1;3(2).
Butala, N. M., et al. “Use of Calcium Modification During Percutaneous Coronary Intervention After Introduction of Coronary Intravascular Lithotripsy.” Journal of the Society for Cardiovascular Angiography and Interventions, vol. 3, no. 2, Feb. 2024. Scopus, doi:10.1016/j.jscai.2023.101254.
Butala NM, Waldo SW, Secemsky EA, Kennedy KF, Spertus JA, Rymer JA, Rao SV, Messenger JC, Yeh RW. Use of Calcium Modification During Percutaneous Coronary Intervention After Introduction of Coronary Intravascular Lithotripsy. Journal of the Society for Cardiovascular Angiography and Interventions. 2024 Feb 1;3(2).

Published In

Journal of the Society for Cardiovascular Angiography and Interventions

DOI

EISSN

2772-9303

Publication Date

February 1, 2024

Volume

3

Issue

2