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Exploring the Multifaceted Landscape of MASLD: A Comprehensive Synthesis of Recent Studies, from Pathophysiology to Organoids and Beyond.

Publication ,  Journal Article
Soto, A; Spongberg, C; Martinino, A; Giovinazzo, F
Published in: Biomedicines
February 2024

Non-alcoholic fatty liver disease (NAFLD) is a widespread contributor to chronic liver disease globally. A recent consensus on renaming liver disease was established, and metabolic dysfunction-associated steatotic liver disease, MASLD, was chosen as the replacement for NAFLD. The disease's range extends from the less severe MASLD, previously known as non-alcoholic fatty liver (NAFL), to the more intense metabolic dysfunction-associated steatohepatitis (MASH), previously known as non-alcoholic steatohepatitis (NASH), characterized by inflammation and apoptosis. This research project endeavors to comprehensively synthesize the most recent studies on MASLD, encompassing a wide spectrum of topics such as pathophysiology, risk factors, dietary influences, lifestyle management, genetics, epigenetics, therapeutic approaches, and the prospective trajectory of MASLD, particularly exploring its connection with organoids.

Duke Scholars

Published In

Biomedicines

DOI

EISSN

2227-9059

ISSN

2227-9059

Publication Date

February 2024

Volume

12

Issue

2

Start / End Page

397

Related Subject Headings

  • 3404 Medicinal and biomolecular chemistry
  • 3214 Pharmacology and pharmaceutical sciences
  • 3101 Biochemistry and cell biology
 

Citation

APA
Chicago
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MLA
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Soto, A., Spongberg, C., Martinino, A., & Giovinazzo, F. (2024). Exploring the Multifaceted Landscape of MASLD: A Comprehensive Synthesis of Recent Studies, from Pathophysiology to Organoids and Beyond. Biomedicines, 12(2), 397. https://doi.org/10.3390/biomedicines12020397
Soto, Allison, Colby Spongberg, Alessandro Martinino, and Francesco Giovinazzo. “Exploring the Multifaceted Landscape of MASLD: A Comprehensive Synthesis of Recent Studies, from Pathophysiology to Organoids and Beyond.Biomedicines 12, no. 2 (February 2024): 397. https://doi.org/10.3390/biomedicines12020397.
Soto, Allison, et al. “Exploring the Multifaceted Landscape of MASLD: A Comprehensive Synthesis of Recent Studies, from Pathophysiology to Organoids and Beyond.Biomedicines, vol. 12, no. 2, Feb. 2024, p. 397. Epmc, doi:10.3390/biomedicines12020397.

Published In

Biomedicines

DOI

EISSN

2227-9059

ISSN

2227-9059

Publication Date

February 2024

Volume

12

Issue

2

Start / End Page

397

Related Subject Headings

  • 3404 Medicinal and biomolecular chemistry
  • 3214 Pharmacology and pharmaceutical sciences
  • 3101 Biochemistry and cell biology