A guideline on the molecular ecosystem regulating ferroptosis.
Publication
, Journal Article
Dai, E; Chen, X; Linkermann, A; Jiang, X; Kang, R; Kagan, VE; Bayir, H; Yang, WS; Garcia-Saez, AJ; Ioannou, MS; Janowitz, T; Ran, Q; Gu, W ...
Published in: Nat Cell Biol
September 2024
Ferroptosis, an intricately regulated form of cell death characterized by uncontrolled lipid peroxidation, has garnered substantial interest since this term was first coined in 2012. Recent years have witnessed remarkable progress in elucidating the detailed molecular mechanisms that govern ferroptosis induction and defence, with particular emphasis on the roles of heterogeneity and plasticity. In this Review, we discuss the molecular ecosystem of ferroptosis, with implications that may inform and enable safe and effective therapeutic strategies across a broad spectrum of diseases.
Duke Scholars
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Published In
Nat Cell Biol
DOI
EISSN
1476-4679
Publication Date
September 2024
Volume
26
Issue
9
Start / End Page
1447 / 1457
Location
England
Related Subject Headings
- Signal Transduction
- Reactive Oxygen Species
- Lipid Peroxidation
- Iron
- Humans
- Ferroptosis
- Developmental Biology
- Animals
- 3101 Biochemistry and cell biology
- 11 Medical and Health Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Dai, E., Chen, X., Linkermann, A., Jiang, X., Kang, R., Kagan, V. E., … Tang, D. (2024). A guideline on the molecular ecosystem regulating ferroptosis. Nat Cell Biol, 26(9), 1447–1457. https://doi.org/10.1038/s41556-024-01360-8
Dai, Enyong, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E. Kagan, Hülya Bayir, et al. “A guideline on the molecular ecosystem regulating ferroptosis.” Nat Cell Biol 26, no. 9 (September 2024): 1447–57. https://doi.org/10.1038/s41556-024-01360-8.
Dai E, Chen X, Linkermann A, Jiang X, Kang R, Kagan VE, et al. A guideline on the molecular ecosystem regulating ferroptosis. Nat Cell Biol. 2024 Sep;26(9):1447–57.
Dai, Enyong, et al. “A guideline on the molecular ecosystem regulating ferroptosis.” Nat Cell Biol, vol. 26, no. 9, Sept. 2024, pp. 1447–57. Pubmed, doi:10.1038/s41556-024-01360-8.
Dai E, Chen X, Linkermann A, Jiang X, Kang R, Kagan VE, Bayir H, Yang WS, Garcia-Saez AJ, Ioannou MS, Janowitz T, Ran Q, Gu W, Gan B, Krysko DV, Zhu X, Wang J, Krautwald S, Toyokuni S, Xie Y, Greten FR, Yi Q, Schick J, Liu J, Gabrilovich DI, Zeh HJ, Zhang DD, Yang M, Iovanna J, Kopf M, Adolph TE, Chi J-T, Li C, Ichijo H, Karin M, Sankaran VG, Zou W, Galluzzi L, Bush AI, Li B, Melino G, Baehrecke EH, Lotze MT, Klionsky DJ, Stockwell BR, Kroemer G, Tang D. A guideline on the molecular ecosystem regulating ferroptosis. Nat Cell Biol. 2024 Sep;26(9):1447–1457.
Published In
Nat Cell Biol
DOI
EISSN
1476-4679
Publication Date
September 2024
Volume
26
Issue
9
Start / End Page
1447 / 1457
Location
England
Related Subject Headings
- Signal Transduction
- Reactive Oxygen Species
- Lipid Peroxidation
- Iron
- Humans
- Ferroptosis
- Developmental Biology
- Animals
- 3101 Biochemistry and cell biology
- 11 Medical and Health Sciences