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A guideline on the molecular ecosystem regulating ferroptosis.

Publication ,  Journal Article
Dai, E; Chen, X; Linkermann, A; Jiang, X; Kang, R; Kagan, VE; Bayir, H; Yang, WS; Garcia-Saez, AJ; Ioannou, MS; Janowitz, T; Ran, Q; Gu, W ...
Published in: Nat Cell Biol
February 29, 2024

Ferroptosis, an intricately regulated form of cell death characterized by uncontrolled lipid peroxidation, has garnered substantial interest since this term was first coined in 2012. Recent years have witnessed remarkable progress in elucidating the detailed molecular mechanisms that govern ferroptosis induction and defence, with particular emphasis on the roles of heterogeneity and plasticity. In this Review, we discuss the molecular ecosystem of ferroptosis, with implications that may inform and enable safe and effective therapeutic strategies across a broad spectrum of diseases.

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Published In

Nat Cell Biol

DOI

EISSN

1476-4679

Publication Date

February 29, 2024

Location

England

Related Subject Headings

  • Developmental Biology
  • 3101 Biochemistry and cell biology
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
 

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Dai, E., Chen, X., Linkermann, A., Jiang, X., Kang, R., Kagan, V. E., … Tang, D. (2024). A guideline on the molecular ecosystem regulating ferroptosis. Nat Cell Biol. https://doi.org/10.1038/s41556-024-01360-8
Dai, Enyong, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E. Kagan, Hülya Bayir, et al. “A guideline on the molecular ecosystem regulating ferroptosis.Nat Cell Biol, February 29, 2024. https://doi.org/10.1038/s41556-024-01360-8.
Dai E, Chen X, Linkermann A, Jiang X, Kang R, Kagan VE, et al. A guideline on the molecular ecosystem regulating ferroptosis. Nat Cell Biol. 2024 Feb 29;
Dai, Enyong, et al. “A guideline on the molecular ecosystem regulating ferroptosis.Nat Cell Biol, Feb. 2024. Pubmed, doi:10.1038/s41556-024-01360-8.
Dai E, Chen X, Linkermann A, Jiang X, Kang R, Kagan VE, Bayir H, Yang WS, Garcia-Saez AJ, Ioannou MS, Janowitz T, Ran Q, Gu W, Gan B, Krysko DV, Zhu X, Wang J, Krautwald S, Toyokuni S, Xie Y, Greten FR, Yi Q, Schick J, Liu J, Gabrilovich DI, Zeh HJ, Zhang DD, Yang M, Iovanna J, Kopf M, Adolph TE, Chi J-T, Li C, Ichijo H, Karin M, Sankaran VG, Zou W, Galluzzi L, Bush AI, Li B, Melino G, Baehrecke EH, Lotze MT, Klionsky DJ, Stockwell BR, Kroemer G, Tang D. A guideline on the molecular ecosystem regulating ferroptosis. Nat Cell Biol. 2024 Feb 29;

Published In

Nat Cell Biol

DOI

EISSN

1476-4679

Publication Date

February 29, 2024

Location

England

Related Subject Headings

  • Developmental Biology
  • 3101 Biochemistry and cell biology
  • 11 Medical and Health Sciences
  • 06 Biological Sciences