
Application of Data-Driven computing to patient-specific prediction of the viscoelastic response of human brain under transcranial ultrasound stimulation.
Publication
, Journal Article
Salahshoor, H; Ortiz, M
Published in: Biomechanics and modeling in mechanobiology
August 2024
We present a class of model-free Data-Driven solvers that effectively enable the utilization of in situ and in vivo imaging data directly in full-scale calculations of the mechanical response of the human brain to sonic and ultrasonic stimulation, entirely bypassing the need for analytical modeling or regression of the data. The well-posedness of the approach and its convergence with respect to data are proven analytically. We demonstrate the approach, including its ability to make detailed spatially resolved patient-specific predictions of wave patterns, using public-domain MRI images, MRE data and commercially available solid-mechanics software.
Duke Scholars
Published In
Biomechanics and modeling in mechanobiology
DOI
EISSN
1617-7940
ISSN
1617-7959
Publication Date
August 2024
Volume
23
Issue
4
Start / End Page
1161 / 1177
Related Subject Headings
- Viscosity
- Ultrasonic Waves
- Software
- Magnetic Resonance Imaging
- Humans
- Elasticity
- Computer Simulation
- Brain
- Biomedical Engineering
- 4003 Biomedical engineering
Citation
APA
Chicago
ICMJE
MLA
NLM
Salahshoor, H., & Ortiz, M. (2024). Application of Data-Driven computing to patient-specific prediction of the viscoelastic response of human brain under transcranial ultrasound stimulation. Biomechanics and Modeling in Mechanobiology, 23(4), 1161–1177. https://doi.org/10.1007/s10237-024-01830-w
Salahshoor, Hossein, and Michael Ortiz. “Application of Data-Driven computing to patient-specific prediction of the viscoelastic response of human brain under transcranial ultrasound stimulation.” Biomechanics and Modeling in Mechanobiology 23, no. 4 (August 2024): 1161–77. https://doi.org/10.1007/s10237-024-01830-w.
Salahshoor H, Ortiz M. Application of Data-Driven computing to patient-specific prediction of the viscoelastic response of human brain under transcranial ultrasound stimulation. Biomechanics and modeling in mechanobiology. 2024 Aug;23(4):1161–77.
Salahshoor, Hossein, and Michael Ortiz. “Application of Data-Driven computing to patient-specific prediction of the viscoelastic response of human brain under transcranial ultrasound stimulation.” Biomechanics and Modeling in Mechanobiology, vol. 23, no. 4, Aug. 2024, pp. 1161–77. Epmc, doi:10.1007/s10237-024-01830-w.
Salahshoor H, Ortiz M. Application of Data-Driven computing to patient-specific prediction of the viscoelastic response of human brain under transcranial ultrasound stimulation. Biomechanics and modeling in mechanobiology. 2024 Aug;23(4):1161–1177.

Published In
Biomechanics and modeling in mechanobiology
DOI
EISSN
1617-7940
ISSN
1617-7959
Publication Date
August 2024
Volume
23
Issue
4
Start / End Page
1161 / 1177
Related Subject Headings
- Viscosity
- Ultrasonic Waves
- Software
- Magnetic Resonance Imaging
- Humans
- Elasticity
- Computer Simulation
- Brain
- Biomedical Engineering
- 4003 Biomedical engineering