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Application of Data-Driven computing to patient-specific prediction of the viscoelastic response of human brain under transcranial ultrasound stimulation.

Publication ,  Journal Article
Salahshoor, H; Ortiz, M
Published in: Biomechanics and modeling in mechanobiology
August 2024

We present a class of model-free Data-Driven solvers that effectively enable the utilization of in situ and in vivo imaging data directly in full-scale calculations of the mechanical response of the human brain to sonic and ultrasonic stimulation, entirely bypassing the need for analytical modeling or regression of the data. The well-posedness of the approach and its convergence with respect to data are proven analytically. We demonstrate the approach, including its ability to make detailed spatially resolved patient-specific predictions of wave patterns, using public-domain MRI images, MRE data and commercially available solid-mechanics software.

Duke Scholars

Published In

Biomechanics and modeling in mechanobiology

DOI

EISSN

1617-7940

ISSN

1617-7959

Publication Date

August 2024

Volume

23

Issue

4

Start / End Page

1161 / 1177

Related Subject Headings

  • Viscosity
  • Ultrasonic Waves
  • Software
  • Magnetic Resonance Imaging
  • Humans
  • Elasticity
  • Computer Simulation
  • Brain
  • Biomedical Engineering
  • 4003 Biomedical engineering
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Salahshoor, H., & Ortiz, M. (2024). Application of Data-Driven computing to patient-specific prediction of the viscoelastic response of human brain under transcranial ultrasound stimulation. Biomechanics and Modeling in Mechanobiology, 23(4), 1161–1177. https://doi.org/10.1007/s10237-024-01830-w
Salahshoor, Hossein, and Michael Ortiz. “Application of Data-Driven computing to patient-specific prediction of the viscoelastic response of human brain under transcranial ultrasound stimulation.Biomechanics and Modeling in Mechanobiology 23, no. 4 (August 2024): 1161–77. https://doi.org/10.1007/s10237-024-01830-w.
Salahshoor, Hossein, and Michael Ortiz. “Application of Data-Driven computing to patient-specific prediction of the viscoelastic response of human brain under transcranial ultrasound stimulation.Biomechanics and Modeling in Mechanobiology, vol. 23, no. 4, Aug. 2024, pp. 1161–77. Epmc, doi:10.1007/s10237-024-01830-w.
Journal cover image

Published In

Biomechanics and modeling in mechanobiology

DOI

EISSN

1617-7940

ISSN

1617-7959

Publication Date

August 2024

Volume

23

Issue

4

Start / End Page

1161 / 1177

Related Subject Headings

  • Viscosity
  • Ultrasonic Waves
  • Software
  • Magnetic Resonance Imaging
  • Humans
  • Elasticity
  • Computer Simulation
  • Brain
  • Biomedical Engineering
  • 4003 Biomedical engineering