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Emotional and functional well-being in long-term breast cancer survivorship.

Publication ,  Journal Article
Ren, Y; Maselko, J; Tan, X; Olshan, AF; Stover, AM; Bennett, AV; Reeder-Hayes, KE; Edwards, JK; Reeve, BB; Troester, MA; Emerson, MA
Published in: Cancer Causes Control
April 20, 2024

PURPOSE: Emotional and functional well-being (EWB and FWB) are important components of mental health and quality of life. This study aims to evaluate long-term EWB and FWB in breast cancer (BC) survivors. METHODS: The Carolina Breast Cancer Study Phase 3 oversampled Black and younger (< 50 years in age) women so that they each represent approximately 50% of the study population and assessed participants' EWB and FWB with the Functional Assessment of Cancer Therapy-Breast (FACT-B) at 5- (baseline), 25-, and 84-months post diagnosis. Multinomial logit models were used to estimate adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for associations between demographic and clinical characteristics and well-being change relative to baseline. RESULTS: Among 2,781 participants with BC, average EWB and FWB improved with time since diagnosis. Persistent FWB decrements were associated with Black race [OR 1.4 (95% CI 1.2-1.7) and 1.3 (95% CI 1.1-1.6), at 25-months and 84-months respectively], older age [OR 1.4 (95% CI 1.1-1.7) and 1.5 (95% CI 1.2-1.8), respectively], no chemotherapy, and recurrence [OR 2.9 (95% CI 1.8-4.8) and 3.1 (95% CI 2.1-4.6), respectively]. EWB decrements were associated with advanced stage and recurrence. Decrements in combined (FWB+EWB) well-being were associated with recurrence at both follow-up survey timepoints [ORs 4.7 (95% CI 2.7-8.0) and 4.3 (95% CI 2.8-6.6), respectively]. CONCLUSIONS: Long-term well-being varies by demographics and clinical features, with Black women and women with aggressive disease at greatest risk of long-term decrements.

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Published In

Cancer Causes Control

DOI

EISSN

1573-7225

Publication Date

April 20, 2024

Location

Netherlands

Related Subject Headings

  • Epidemiology
  • 4202 Epidemiology
  • 3211 Oncology and carcinogenesis
  • 1117 Public Health and Health Services
  • 1112 Oncology and Carcinogenesis
 

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Ren, Y., Maselko, J., Tan, X., Olshan, A. F., Stover, A. M., Bennett, A. V., … Emerson, M. A. (2024). Emotional and functional well-being in long-term breast cancer survivorship. Cancer Causes Control. https://doi.org/10.1007/s10552-024-01877-1
Ren, Yumeng, Joanna Maselko, Xianming Tan, Andrew F. Olshan, Angela M. Stover, Antonia V. Bennett, Katherine E. Reeder-Hayes, et al. “Emotional and functional well-being in long-term breast cancer survivorship.Cancer Causes Control, April 20, 2024. https://doi.org/10.1007/s10552-024-01877-1.
Ren Y, Maselko J, Tan X, Olshan AF, Stover AM, Bennett AV, et al. Emotional and functional well-being in long-term breast cancer survivorship. Cancer Causes Control. 2024 Apr 20;
Ren, Yumeng, et al. “Emotional and functional well-being in long-term breast cancer survivorship.Cancer Causes Control, Apr. 2024. Pubmed, doi:10.1007/s10552-024-01877-1.
Ren Y, Maselko J, Tan X, Olshan AF, Stover AM, Bennett AV, Reeder-Hayes KE, Edwards JK, Reeve BB, Troester MA, Emerson MA. Emotional and functional well-being in long-term breast cancer survivorship. Cancer Causes Control. 2024 Apr 20;
Journal cover image

Published In

Cancer Causes Control

DOI

EISSN

1573-7225

Publication Date

April 20, 2024

Location

Netherlands

Related Subject Headings

  • Epidemiology
  • 4202 Epidemiology
  • 3211 Oncology and carcinogenesis
  • 1117 Public Health and Health Services
  • 1112 Oncology and Carcinogenesis