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Ketamine Use for Palliative Care in the Austere Environment: Is Ketamine the Path Forward for Palliative Care.

Publication ,  Journal Article
Reed, JR; Parks, SK; Kaniaru, A; Hefley, J; Yauger, Y; Edwards, JV; Glymph, DC
Published in: The American journal of hospice & palliative care
March 2025

The goal of palliative care is to focus on the holistic needs of the patient and their family versus the pathology of the patient's diagnosis to reduce the stress of illness. U.S. servicemembers deployed to austere environments worldwide have significantly less access to palliative care than in military treatment facilities in the U.S. Preparation for future conflicts introduces the concept of prolonged medical management for an environment where urgent casualty evacuation is impossible. Ketamine is currently widely used for analgesia and anesthesia in the care of military service members and its use has increased in combat zones of Iraq and Afghanistan due to the favorable preservation of respiratory function, minimal changes in hemodynamics, and lower pain scores compared to opioids. Ketamine acts as a non-competitive antagonist on N-methyl-D aspartate (NMDA) receptors. Its anesthesia and analgesic effects are complex and include both presynaptic and postsynaptic neurons in brain and spinal cord. The use of palliative care to minimize suffering should not be withheld due to the logistical boundaries of austere military environments or lack of guidelines for recommended use. The use of ketamine for palliative care is a new clinical management strategy to provide both sedation and pain management for an acute pain crisis or comfort measures for the terminally ill. This makes ketamine an attractive consideration for palliative care when managing critically wounded patients for an extended time.

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Published In

The American journal of hospice & palliative care

DOI

EISSN

1938-2715

ISSN

1049-9091

Publication Date

March 2025

Volume

42

Issue

3

Start / End Page

225 / 229

Related Subject Headings

  • United States
  • Resource-Limited Settings
  • Receptors, N-Methyl-D-Aspartate
  • Palliative Care
  • Pain Management
  • Pain
  • Military Personnel
  • Ketamine
  • Humans
  • Gerontology
 

Citation

APA
Chicago
ICMJE
MLA
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Reed, J. R., Parks, S. K., Kaniaru, A., Hefley, J., Yauger, Y., Edwards, J. V., & Glymph, D. C. (2025). Ketamine Use for Palliative Care in the Austere Environment: Is Ketamine the Path Forward for Palliative Care. The American Journal of Hospice & Palliative Care, 42(3), 225–229. https://doi.org/10.1177/10499091241246520
Reed, John R., Stephanie K. Parks, Antony Kaniaru, Justin Hefley, Young Yauger, Jeremy V. Edwards, and Derrick C. Glymph. “Ketamine Use for Palliative Care in the Austere Environment: Is Ketamine the Path Forward for Palliative Care.The American Journal of Hospice & Palliative Care 42, no. 3 (March 2025): 225–29. https://doi.org/10.1177/10499091241246520.
Reed JR, Parks SK, Kaniaru A, Hefley J, Yauger Y, Edwards JV, et al. Ketamine Use for Palliative Care in the Austere Environment: Is Ketamine the Path Forward for Palliative Care. The American journal of hospice & palliative care. 2025 Mar;42(3):225–9.
Reed, John R., et al. “Ketamine Use for Palliative Care in the Austere Environment: Is Ketamine the Path Forward for Palliative Care.The American Journal of Hospice & Palliative Care, vol. 42, no. 3, Mar. 2025, pp. 225–29. Epmc, doi:10.1177/10499091241246520.
Reed JR, Parks SK, Kaniaru A, Hefley J, Yauger Y, Edwards JV, Glymph DC. Ketamine Use for Palliative Care in the Austere Environment: Is Ketamine the Path Forward for Palliative Care. The American journal of hospice & palliative care. 2025 Mar;42(3):225–229.
Journal cover image

Published In

The American journal of hospice & palliative care

DOI

EISSN

1938-2715

ISSN

1049-9091

Publication Date

March 2025

Volume

42

Issue

3

Start / End Page

225 / 229

Related Subject Headings

  • United States
  • Resource-Limited Settings
  • Receptors, N-Methyl-D-Aspartate
  • Palliative Care
  • Pain Management
  • Pain
  • Military Personnel
  • Ketamine
  • Humans
  • Gerontology