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Methodological issues in clinical drug development for essential tremor

Publication ,  Journal Article
Carranza, MA; Snyder, MR; Elble, RJ; Boutzoukas, AE; Zesiewicz, TA
Published in: Tremor and Other Hyperkinetic Movements
January 1, 2012

Essential tremor (ET) is one of the most common tremor disorders in the world. Despite this, only two medications have received Level A recommendations from the American Academy of Neurology to treat it (primidone and propranolol). Even though these medications provide relief to a large group of ET patients, up to 50% of patients are non-responders. Additional medications to treat ET are needed. This review discusses some of the methodological issues that should be addressed for quality clinical drug development in ET.

Duke Scholars

Published In

Tremor and Other Hyperkinetic Movements

DOI

EISSN

2160-8288

Publication Date

January 1, 2012

Volume

2
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Carranza, M. A., Snyder, M. R., Elble, R. J., Boutzoukas, A. E., & Zesiewicz, T. A. (2012). Methodological issues in clinical drug development for essential tremor. Tremor and Other Hyperkinetic Movements, 2. https://doi.org/10.5334/TOHM.116
Carranza, M. A., M. R. Snyder, R. J. Elble, A. E. Boutzoukas, and T. A. Zesiewicz. “Methodological issues in clinical drug development for essential tremor.” Tremor and Other Hyperkinetic Movements 2 (January 1, 2012). https://doi.org/10.5334/TOHM.116.
Carranza MA, Snyder MR, Elble RJ, Boutzoukas AE, Zesiewicz TA. Methodological issues in clinical drug development for essential tremor. Tremor and Other Hyperkinetic Movements. 2012 Jan 1;2.
Carranza, M. A., et al. “Methodological issues in clinical drug development for essential tremor.” Tremor and Other Hyperkinetic Movements, vol. 2, Jan. 2012. Scopus, doi:10.5334/TOHM.116.
Carranza MA, Snyder MR, Elble RJ, Boutzoukas AE, Zesiewicz TA. Methodological issues in clinical drug development for essential tremor. Tremor and Other Hyperkinetic Movements. 2012 Jan 1;2.

Published In

Tremor and Other Hyperkinetic Movements

DOI

EISSN

2160-8288

Publication Date

January 1, 2012

Volume

2