Relapsing malignant phyllodes tumour presenting as isolated acrometastases.
Malignant phyllodes tumours (PTs) are aggressive neoplasms with high rates of local recurrence and distant metastasis. With no known effective chemotherapy and no approved targeted therapy in the setting of metastatic disease, prognosis is limited with an often-relapsing course of disease. We report a case of a woman in her late 30s with a diagnosis of recurrent metastatic malignant PT who was found to have acrometastases of the malignant PT to the right distal index and small digits. We emphasise the potential for atypical patterns of metastases in patients with malignant PT and the need to recognise acrometastasis as an unusual but morbid manifestation of disease. Given the high growth rate of malignant PTs, the lack of systemic treatment options, and the ensuing distress for patients, prompt diagnosis and early intervention is crucial.
Duke Scholars
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Related Subject Headings
- Phyllodes Tumor
- Neoplasm Recurrence, Local
- Humans
- Female
- Breast Neoplasms
- Bone Neoplasms
- Adult
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 1103 Clinical Sciences
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Location
Related Subject Headings
- Phyllodes Tumor
- Neoplasm Recurrence, Local
- Humans
- Female
- Breast Neoplasms
- Bone Neoplasms
- Adult
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 1103 Clinical Sciences