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Lumbar Discitis and Osteomyelitis After a Spinal Stem Cell Injection?: A Case Report and Literature Review.

Publication ,  Journal Article
Ramos, O; Speirs, JN; Danisa, O
Published in: JBJS Case Connect
2020

CASE: A 32-year-old man developed lumbar discitis and osteomyelitis after receiving a cell-based injection for the treatment of degenerative disc disease. Initial cultures were negative, but he continued to worsen, and a repeat set of cultures was taken. On day 10, Cutibacterium acnes was isolated. He was then successfully treated with 12 weeks of intravenous antibiotics. CONCLUSIONS: There is minimal regulation on the preparation or administration of cell-based interventions. It is important to consider slow growing organisms such as C. acnes in patients presenting with spinal infection with insidious onset after these treatments.

Duke Scholars

Published In

JBJS Case Connect

DOI

EISSN

2160-3251

Publication Date

2020

Volume

10

Issue

3

Start / End Page

e19.00636

Location

United States

Related Subject Headings

  • Transplantation, Autologous
  • Technetium Tc 99m Exametazime
  • Stem Cell Transplantation
  • Radionuclide Imaging
  • Propionibacteriaceae
  • Osteomyelitis
  • Male
  • Magnetic Resonance Imaging
  • Intervertebral Disc Displacement
  • Intervertebral Disc Degeneration
 

Citation

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Ramos, O., Speirs, J. N., & Danisa, O. (2020). Lumbar Discitis and Osteomyelitis After a Spinal Stem Cell Injection?: A Case Report and Literature Review. JBJS Case Connect, 10(3), e19.00636. https://doi.org/10.2106/JBJS.CC.19.00636
Ramos, Omar, Joshua N. Speirs, and Olumide Danisa. “Lumbar Discitis and Osteomyelitis After a Spinal Stem Cell Injection?: A Case Report and Literature Review.JBJS Case Connect 10, no. 3 (2020): e19.00636. https://doi.org/10.2106/JBJS.CC.19.00636.
Ramos, Omar, et al. “Lumbar Discitis and Osteomyelitis After a Spinal Stem Cell Injection?: A Case Report and Literature Review.JBJS Case Connect, vol. 10, no. 3, 2020, p. e19.00636. Pubmed, doi:10.2106/JBJS.CC.19.00636.

Published In

JBJS Case Connect

DOI

EISSN

2160-3251

Publication Date

2020

Volume

10

Issue

3

Start / End Page

e19.00636

Location

United States

Related Subject Headings

  • Transplantation, Autologous
  • Technetium Tc 99m Exametazime
  • Stem Cell Transplantation
  • Radionuclide Imaging
  • Propionibacteriaceae
  • Osteomyelitis
  • Male
  • Magnetic Resonance Imaging
  • Intervertebral Disc Displacement
  • Intervertebral Disc Degeneration