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Lumbar Discitis and Osteomyelitis After a Spinal Stem Cell Injection?: A Case Report and Literature Review.

Publication ,  Journal Article
Ramos, O; Speirs, JN; Danisa, O
Published in: JBJS case connector
July 2020

A 32-year-old man developed lumbar discitis and osteomyelitis after receiving a cell-based injection for the treatment of degenerative disc disease. Initial cultures were negative, but he continued to worsen, and a repeat set of cultures was taken. On day 10, Cutibacterium acnes was isolated. He was then successfully treated with 12 weeks of intravenous antibiotics.There is minimal regulation on the preparation or administration of cell-based interventions. It is important to consider slow growing organisms such as C. acnes in patients presenting with spinal infection with insidious onset after these treatments.

Duke Scholars

Published In

JBJS case connector

DOI

EISSN

2160-3251

ISSN

2160-3251

Publication Date

July 2020

Volume

10

Issue

3

Start / End Page

e19.00636

Related Subject Headings

  • Transplantation, Autologous
  • Technetium Tc 99m Exametazime
  • Stem Cell Transplantation
  • Radionuclide Imaging
  • Propionibacteriaceae
  • Osteomyelitis
  • Male
  • Magnetic Resonance Imaging
  • Intervertebral Disc Displacement
  • Intervertebral Disc Degeneration
 

Citation

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Ramos, O., Speirs, J. N., & Danisa, O. (2020). Lumbar Discitis and Osteomyelitis After a Spinal Stem Cell Injection?: A Case Report and Literature Review. JBJS Case Connector, 10(3), e19.00636. https://doi.org/10.2106/jbjs.cc.19.00636
Ramos, Omar, Joshua N. Speirs, and Olumide Danisa. “Lumbar Discitis and Osteomyelitis After a Spinal Stem Cell Injection?: A Case Report and Literature Review.JBJS Case Connector 10, no. 3 (July 2020): e19.00636. https://doi.org/10.2106/jbjs.cc.19.00636.
Ramos O, Speirs JN, Danisa O. Lumbar Discitis and Osteomyelitis After a Spinal Stem Cell Injection?: A Case Report and Literature Review. JBJS case connector. 2020 Jul;10(3):e19.00636.
Ramos, Omar, et al. “Lumbar Discitis and Osteomyelitis After a Spinal Stem Cell Injection?: A Case Report and Literature Review.JBJS Case Connector, vol. 10, no. 3, July 2020, p. e19.00636. Epmc, doi:10.2106/jbjs.cc.19.00636.
Ramos O, Speirs JN, Danisa O. Lumbar Discitis and Osteomyelitis After a Spinal Stem Cell Injection?: A Case Report and Literature Review. JBJS case connector. 2020 Jul;10(3):e19.00636.

Published In

JBJS case connector

DOI

EISSN

2160-3251

ISSN

2160-3251

Publication Date

July 2020

Volume

10

Issue

3

Start / End Page

e19.00636

Related Subject Headings

  • Transplantation, Autologous
  • Technetium Tc 99m Exametazime
  • Stem Cell Transplantation
  • Radionuclide Imaging
  • Propionibacteriaceae
  • Osteomyelitis
  • Male
  • Magnetic Resonance Imaging
  • Intervertebral Disc Displacement
  • Intervertebral Disc Degeneration