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Exploring Revision Total Ankle Arthroplasty Failures: A Comparison Between Failed and Successful Revision Cases.

Publication ,  Journal Article
Wu, KA; Anastasio, AT; DeOrio, JK; Nunley, JA; Easley, ME; Adams, SB
Published in: Foot Ankle Spec
June 2025

This study assesses the comorbidities that are associated with failed revision total ankle arthroplasty (TAA) and explores the outcomes following a failed revision TAA. A retrospective analysis was conducted on a cohort of patients who underwent a revision TAA at a single institution from 2008 to 2022. Patients were identified as having revision failure if they required explantation, below-knee amputation (BKA), or a revision of either metal component. Statistical analysis was performed to identify any significant differences and summarize outcomes. The study included a total of 87 patients who underwent revision TAA with 12 patients who subsequently experienced revision failure. The revision TAA failure rate was 13.8%. There were higher rates of former smokers (58.3%; n = 7) and a history of diabetes (33.3%; n = 4) in the failure cohort, although these differences did not reach statistical significance. Limb salvage procedures were achieved in 11 cases (91.7%). Approaches for failed revision TAAs included arthrodesis (n = 5) with 2 isolated ankle arthrodesis (AA) and 3 tibio-talo-calcaneal (TTC) arthrodesis, an additional revision arthroplasty (n = 6), or amputation (n = 1). Ankle arthroplasty retention was successful in 6 cases (50.0%). Our results demonstrate that a second revision approach was chosen in half of the cases, underscoring its viability as a successful intervention according to patient preferences.Level of Evidence: III.

Duke Scholars

Published In

Foot Ankle Spec

DOI

EISSN

1938-7636

Publication Date

June 2025

Volume

18

Issue

3

Start / End Page

286 / 294

Location

United States

Related Subject Headings

  • Treatment Failure
  • Retrospective Studies
  • Reoperation
  • Prosthesis Failure
  • Middle Aged
  • Male
  • Limb Salvage
  • Humans
  • Female
  • Arthroplasty, Replacement, Ankle
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Wu, K. A., Anastasio, A. T., DeOrio, J. K., Nunley, J. A., Easley, M. E., & Adams, S. B. (2025). Exploring Revision Total Ankle Arthroplasty Failures: A Comparison Between Failed and Successful Revision Cases. Foot Ankle Spec, 18(3), 286–294. https://doi.org/10.1177/19386400241274551
Wu, Kevin A., Albert T. Anastasio, James K. DeOrio, James A. Nunley, Mark E. Easley, and Samuel B. Adams. “Exploring Revision Total Ankle Arthroplasty Failures: A Comparison Between Failed and Successful Revision Cases.Foot Ankle Spec 18, no. 3 (June 2025): 286–94. https://doi.org/10.1177/19386400241274551.
Wu KA, Anastasio AT, DeOrio JK, Nunley JA, Easley ME, Adams SB. Exploring Revision Total Ankle Arthroplasty Failures: A Comparison Between Failed and Successful Revision Cases. Foot Ankle Spec. 2025 Jun;18(3):286–94.
Wu, Kevin A., et al. “Exploring Revision Total Ankle Arthroplasty Failures: A Comparison Between Failed and Successful Revision Cases.Foot Ankle Spec, vol. 18, no. 3, June 2025, pp. 286–94. Pubmed, doi:10.1177/19386400241274551.
Wu KA, Anastasio AT, DeOrio JK, Nunley JA, Easley ME, Adams SB. Exploring Revision Total Ankle Arthroplasty Failures: A Comparison Between Failed and Successful Revision Cases. Foot Ankle Spec. 2025 Jun;18(3):286–294.
Journal cover image

Published In

Foot Ankle Spec

DOI

EISSN

1938-7636

Publication Date

June 2025

Volume

18

Issue

3

Start / End Page

286 / 294

Location

United States

Related Subject Headings

  • Treatment Failure
  • Retrospective Studies
  • Reoperation
  • Prosthesis Failure
  • Middle Aged
  • Male
  • Limb Salvage
  • Humans
  • Female
  • Arthroplasty, Replacement, Ankle