Mei-p26 cooperates with Bam, Bgcn and Sxl to promote early germline development in the Drosophila ovary.
Publication
, Journal Article
Li, Y; Zhang, Q; Carreira-Rosario, A; Maines, JZ; McKearin, DM; Buszczak, M
Published in: PloS one
January 2013
In the Drosophila female germline, spatially and temporally specific translation of mRNAs governs both stem cell maintenance and the differentiation of their progeny. However, the mechanisms that control and coordinate different modes of translational repression within this lineage remain incompletely understood. Here we present data showing that Mei-P26 associates with Bam, Bgcn and Sxl and nanos mRNA during early cyst development, suggesting that this protein helps to repress the translation of nanos mRNA. Together with recently published studies, these data suggest that Mei-P26 mediates both GSC self-renewal and germline differentiation through distinct modes of translational repression depending on the presence of Bam.
Duke Scholars
Published In
PloS one
DOI
EISSN
1932-6203
ISSN
1932-6203
Publication Date
January 2013
Volume
8
Issue
3
Start / End Page
e58301
Related Subject Headings
- RNA-Binding Proteins
- RNA, Messenger
- Ovum
- Ovary
- General Science & Technology
- Gene Expression Regulation, Developmental
- Female
- Embryonic Stem Cells
- Drosophila melanogaster
- Drosophila Proteins
Citation
APA
Chicago
ICMJE
MLA
NLM
Li, Y., Zhang, Q., Carreira-Rosario, A., Maines, J. Z., McKearin, D. M., & Buszczak, M. (2013). Mei-p26 cooperates with Bam, Bgcn and Sxl to promote early germline development in the Drosophila ovary. PloS One, 8(3), e58301. https://doi.org/10.1371/journal.pone.0058301
Li, Yun, Qiao Zhang, Arnaldo Carreira-Rosario, Jean Z. Maines, Dennis M. McKearin, and Michael Buszczak. “Mei-p26 cooperates with Bam, Bgcn and Sxl to promote early germline development in the Drosophila ovary.” PloS One 8, no. 3 (January 2013): e58301. https://doi.org/10.1371/journal.pone.0058301.
Li Y, Zhang Q, Carreira-Rosario A, Maines JZ, McKearin DM, Buszczak M. Mei-p26 cooperates with Bam, Bgcn and Sxl to promote early germline development in the Drosophila ovary. PloS one. 2013 Jan;8(3):e58301.
Li, Yun, et al. “Mei-p26 cooperates with Bam, Bgcn and Sxl to promote early germline development in the Drosophila ovary.” PloS One, vol. 8, no. 3, Jan. 2013, p. e58301. Epmc, doi:10.1371/journal.pone.0058301.
Li Y, Zhang Q, Carreira-Rosario A, Maines JZ, McKearin DM, Buszczak M. Mei-p26 cooperates with Bam, Bgcn and Sxl to promote early germline development in the Drosophila ovary. PloS one. 2013 Jan;8(3):e58301.
Published In
PloS one
DOI
EISSN
1932-6203
ISSN
1932-6203
Publication Date
January 2013
Volume
8
Issue
3
Start / End Page
e58301
Related Subject Headings
- RNA-Binding Proteins
- RNA, Messenger
- Ovum
- Ovary
- General Science & Technology
- Gene Expression Regulation, Developmental
- Female
- Embryonic Stem Cells
- Drosophila melanogaster
- Drosophila Proteins