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Sacroiliac joint dysfunction: anatomy, pathophysiology, differential diagnosis, and treatment approaches.

Publication ,  Journal Article
Waldman, LE; Maluli, I; Moon, CN; Skalski, M; Matcuk, GR
Published in: Skeletal Radiol
June 2025

The sacroiliac joints (SIJ) play a pivotal role in pelvic stability and load transmission. SIJ-related disorders can pose a diagnostic challenge because of complex anatomy, non-specific imaging findings, and overlapping symptomatology with other lower back conditions. Broadly, SIJ pathology can be divided into the following categories: infectious, inflammatory, degenerative, mechanical, traumatic, and neoplastic. On the spectrum of mechanical disorders is the entity of SIJ dysfunction, defined as pain localized to the SIJ due to non-inflammatory causes. This paper aims to enhance the understanding of SIJ dysfunction by exploring SIJ anatomy, pathophysiology, and differential diagnosis for SIJ pain. Etiologies, associations, and diagnostic physical examination maneuvers for SIJ dysfunction are reviewed. We will discuss the role of diagnostic imaging in SIJ dysfunction and propose imaging findings which may indicate the diagnosis. Finally, we will discuss therapeutic strategies to treat SIJ dysfunction. By delving into the complexities of SIJ anatomy and pathophysiology, this paper provides valuable discernment for the diagnosis and management of SIJ-related disorders.

Duke Scholars

Published In

Skeletal Radiol

DOI

EISSN

1432-2161

Publication Date

June 2025

Volume

54

Issue

6

Start / End Page

1195 / 1213

Location

Germany

Related Subject Headings

  • Sacroiliac Joint
  • Nuclear Medicine & Medical Imaging
  • Joint Diseases
  • Humans
  • Diagnosis, Differential
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Waldman, L. E., Maluli, I., Moon, C. N., Skalski, M., & Matcuk, G. R. (2025). Sacroiliac joint dysfunction: anatomy, pathophysiology, differential diagnosis, and treatment approaches. Skeletal Radiol, 54(6), 1195–1213. https://doi.org/10.1007/s00256-024-04831-z
Waldman, Leah E., Isabela Maluli, Charles N. Moon, Matthew Skalski, and George R. Matcuk. “Sacroiliac joint dysfunction: anatomy, pathophysiology, differential diagnosis, and treatment approaches.Skeletal Radiol 54, no. 6 (June 2025): 1195–1213. https://doi.org/10.1007/s00256-024-04831-z.
Waldman LE, Maluli I, Moon CN, Skalski M, Matcuk GR. Sacroiliac joint dysfunction: anatomy, pathophysiology, differential diagnosis, and treatment approaches. Skeletal Radiol. 2025 Jun;54(6):1195–213.
Waldman, Leah E., et al. “Sacroiliac joint dysfunction: anatomy, pathophysiology, differential diagnosis, and treatment approaches.Skeletal Radiol, vol. 54, no. 6, June 2025, pp. 1195–213. Pubmed, doi:10.1007/s00256-024-04831-z.
Waldman LE, Maluli I, Moon CN, Skalski M, Matcuk GR. Sacroiliac joint dysfunction: anatomy, pathophysiology, differential diagnosis, and treatment approaches. Skeletal Radiol. 2025 Jun;54(6):1195–1213.
Journal cover image

Published In

Skeletal Radiol

DOI

EISSN

1432-2161

Publication Date

June 2025

Volume

54

Issue

6

Start / End Page

1195 / 1213

Location

Germany

Related Subject Headings

  • Sacroiliac Joint
  • Nuclear Medicine & Medical Imaging
  • Joint Diseases
  • Humans
  • Diagnosis, Differential
  • 3202 Clinical sciences
  • 1103 Clinical Sciences