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Surgical Management of Colorectal Cancer Liver Metastases.

Publication ,  Journal Article
Padmanabhan, C; Nussbaum, DP; D'Angelica, M
Published in: Hematol Oncol Clin North Am
February 2025

Approximately 50% of colorectal cancer patients develop liver metastases. Hepatic metastases represent the most common cause of colorectal cancer-related mortality. Metastasectomy, if possible, represents the most effective treatment strategy; 20% of patients will be cured and more than 50% survive at least 5 years. Nuances to treatment planning hinge on whether patients present with resectable disease upfront, whether the future liver remnant is adequate, and whether the primary tumor, if present, is colon versus rectal in origin. This article discusses considerations impacting our approach to patients with colorectal liver metastases and the role for various multimodal treatment options.

Duke Scholars

Published In

Hematol Oncol Clin North Am

DOI

EISSN

1558-1977

Publication Date

February 2025

Volume

39

Issue

1

Start / End Page

1 / 24

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • Metastasectomy
  • Liver Neoplasms
  • Humans
  • Hepatectomy
  • Disease Management
  • Combined Modality Therapy
  • Colorectal Neoplasms
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Padmanabhan, C., Nussbaum, D. P., & D’Angelica, M. (2025). Surgical Management of Colorectal Cancer Liver Metastases. Hematol Oncol Clin North Am, 39(1), 1–24. https://doi.org/10.1016/j.hoc.2024.08.011
Padmanabhan, Chandrasekhar, Daniel P. Nussbaum, and Michael D’Angelica. “Surgical Management of Colorectal Cancer Liver Metastases.Hematol Oncol Clin North Am 39, no. 1 (February 2025): 1–24. https://doi.org/10.1016/j.hoc.2024.08.011.
Padmanabhan C, Nussbaum DP, D’Angelica M. Surgical Management of Colorectal Cancer Liver Metastases. Hematol Oncol Clin North Am. 2025 Feb;39(1):1–24.
Padmanabhan, Chandrasekhar, et al. “Surgical Management of Colorectal Cancer Liver Metastases.Hematol Oncol Clin North Am, vol. 39, no. 1, Feb. 2025, pp. 1–24. Pubmed, doi:10.1016/j.hoc.2024.08.011.
Padmanabhan C, Nussbaum DP, D’Angelica M. Surgical Management of Colorectal Cancer Liver Metastases. Hematol Oncol Clin North Am. 2025 Feb;39(1):1–24.
Journal cover image

Published In

Hematol Oncol Clin North Am

DOI

EISSN

1558-1977

Publication Date

February 2025

Volume

39

Issue

1

Start / End Page

1 / 24

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • Metastasectomy
  • Liver Neoplasms
  • Humans
  • Hepatectomy
  • Disease Management
  • Combined Modality Therapy
  • Colorectal Neoplasms
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology