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Single-position Prone Lateral Interbody Fusion is Associated With Improved Radiographic and Clinical Outcomes at One Year Compared With Single-position Lateral Interbody Fusion: A Single Institution Experience.

Publication ,  Journal Article
Yung, A; Onafowokan, OO; Tretiakov, PS; Fisher, MR; Das, A; Cottrill, EJ; Prado, IP; Ivasyk, I; Blaber, OK; Wu, CM; Williamson, TK; Thomas, Z ...
Published in: Spine (Phila Pa 1976)
October 15, 2025

BACKGROUND: Recent studies highlight the increasing adoption of single-position prone lateral (SP-PL) and single-position lateral decubitus (SP-LD) in minimally invasive spine surgery (MISS) to reduce operative time, enhance patient safety, and improve surgical accessibility. OBJECTIVE: To assess the differences between SP-PL and SP-LD achievement of optimal postoperative outcomes and postoperative complication rates. STUDY DESIGN: Retrospective review of prospectively collected MIS database. MATERIALS AND METHODS: Consecutive series of 152 patients with baseline (BL) and 1-year (1Y) postoperative radiographic/HRQL data were included. Patients placed in the SP-PL or SP-LD were isolated. Optimal outcome (OO) was defined as patients who experienced no complication requiring reoperation and achieved substantial clinical benefit (SCB) for NRS-leg or NRS-back. Means comparison analysis assessed differences in radiographic and clinical outcomes. ANCOVA and multivariable backward stepwise logistic regression were used to adjust for confounders. RESULTS: Totally, 59 SP-PL and 93 SP-LD patients were included. At baseline, cohorts were comparable in terms of age, gender, BMI, and CCI. Perioperatively, SP-PL patients had a significantly lower operative time (207.22 vs . 317.5 min; P <0.001), LOS (3.1 vs . 3.6 d; P =0.033), EBL (244.5 vs . 376.3 mL; P =0.023), and demonstrated lower perioperative complication rate (25.4% vs . 41.9%; P =0.038). Multivariable analysis indicated that SP-PL patients had a lower likelihood of cardiac perioperative complications (OR: 0.012, 95% CI: 0.0-0.6; P =0.026). Immediate postoperatively, SP-PL has a greater degree of segmental lordosis improvement from L1-L2 to L5-S1 (all; P <0.05). SP-PL patients have a higher likelihood of achieving SCB NRS-back at 1Y (OR: 8.0, 95% CI: 1.5-42.0; P =0.014) and MCID NRS-leg at 1Y (OR: 4.6, 95% CI: 1.002-21.2; P =0.49). The SP-PL cohort had a significantly greater percentage of OO (96.6% vs . 78.5%; P =0.002) and a higher likelihood of achieving OO in adjusted analysis (OR: 10.6, 95% CI: 2.1-53.3; P =0.004). CONCLUSIONS: Patients placed in the SP-PL during minimally invasive spine surgery exhibit a reduced rate of perioperative complications, higher incidence of SCB, and a superior rate of achieving optimal outcome at the one-year follow-up. These findings underscore the SP-PL position as a potentially advantageous approach for minimally invasive lumbar fusion.

Duke Scholars

Published In

Spine (Phila Pa 1976)

DOI

EISSN

1528-1159

Publication Date

October 15, 2025

Volume

50

Issue

20

Start / End Page

1427 / 1434

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Spinal Fusion
  • Retrospective Studies
  • Prone Position
  • Postoperative Complications
  • Patient Positioning
  • Orthopedics
  • Minimally Invasive Surgical Procedures
  • Middle Aged
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Yung, A., Onafowokan, O. O., Tretiakov, P. S., Fisher, M. R., Das, A., Cottrill, E. J., … Passias, P. G. (2025). Single-position Prone Lateral Interbody Fusion is Associated With Improved Radiographic and Clinical Outcomes at One Year Compared With Single-position Lateral Interbody Fusion: A Single Institution Experience. Spine (Phila Pa 1976), 50(20), 1427–1434. https://doi.org/10.1097/BRS.0000000000005239
Yung, Anthony, Oluwatobi O. Onafowokan, Peter S. Tretiakov, Max R. Fisher, Ankita Das, Ethan J. Cottrill, Isabel P. Prado, et al. “Single-position Prone Lateral Interbody Fusion is Associated With Improved Radiographic and Clinical Outcomes at One Year Compared With Single-position Lateral Interbody Fusion: A Single Institution Experience.Spine (Phila Pa 1976) 50, no. 20 (October 15, 2025): 1427–34. https://doi.org/10.1097/BRS.0000000000005239.
Yung A, Onafowokan OO, Tretiakov PS, Fisher MR, Das A, Cottrill EJ, Prado IP, Ivasyk I, Blaber OK, Wu CM, Williamson TK, Thomas Z, Crutcher CL, Park P, Schoenfeld AJ, Abd-El-Barr MM, Passias PG. Single-position Prone Lateral Interbody Fusion is Associated With Improved Radiographic and Clinical Outcomes at One Year Compared With Single-position Lateral Interbody Fusion: A Single Institution Experience. Spine (Phila Pa 1976). 2025 Oct 15;50(20):1427–1434.

Published In

Spine (Phila Pa 1976)

DOI

EISSN

1528-1159

Publication Date

October 15, 2025

Volume

50

Issue

20

Start / End Page

1427 / 1434

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Spinal Fusion
  • Retrospective Studies
  • Prone Position
  • Postoperative Complications
  • Patient Positioning
  • Orthopedics
  • Minimally Invasive Surgical Procedures
  • Middle Aged
  • Male